| Psoriasis vulgaris
Ilumya vs Sorilux
Side-by-side clinical, coverage, and cost comparison for psoriasis vulgaris.Deep comparison between: Ilumya vs Sorilux with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsSorilux has a higher rate of injection site reactions vs Ilumya based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Sorilux but not Ilumya, including UnitedHealthcare
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Category
Ilumya
Sorilux
At A Glance
SC injection
Every 12 weeks
IL-23 antagonist
Topical
Twice daily
Synthetic vitamin D3 analog
Indications
- Psoriasis vulgaris
- Psoriasis vulgaris
Dosing
Psoriasis vulgaris 100 mg SC at Weeks 0, 4, and every 12 weeks thereafter.
Psoriasis vulgaris Apply a thin layer twice daily to affected areas and rub in gently and completely; avoid contact with the face and eyes.
Contraindications
- Previous serious hypersensitivity reaction to tildrakizumab-asmn or any excipient
- Known hypercalcemia
Adverse Reactions
Most common (>=1%) Upper respiratory infections, injection site reactions, diarrhea
Serious Hypersensitivity reactions, infections
Most common (>=1%) Application site erythema, application site pain
Postmarketing Application site vesicles
Pharmacology
Tildrakizumab is a humanized IgG1/k monoclonal antibody that selectively binds to the p19 subunit of IL-23 and inhibits its interaction with the IL-23 receptor, thereby suppressing the release of proinflammatory cytokines and chemokines.
Calcipotriene is a synthetic vitamin D3 analog with similar receptor binding affinity as natural vitamin D3; the exact mechanism contributing to clinical efficacy in psoriasis is unknown.
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Most Common Insurance
Anthem BCBS
Ilumya
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (9/12) · Qty limit (9/12)
Sorilux
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (6/12) · Qty limit (9/12)
UnitedHealthcare
Ilumya
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Sorilux
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Humana
Ilumya
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (3/3)
Sorilux
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (2/3) · Qty limit (2/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
Cost estimate not availableAssistance Fund: Psoriasis
Commercial or private insurance
Medicare, Medicaid, VA, TRICARE
Final cost depends on formulary coverage
No savings programs available for Sorilux.
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IlumyaView full Ilumya profile
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Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.