| Psoriasis vulgaris
Lexette vs Wynzora
Side-by-side clinical, coverage, and cost comparison for psoriasis vulgaris.Deep comparison between: Lexette vs Wynzora with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsWynzora has a higher rate of injection site reactions vs Lexette based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Wynzora but not Lexette, including UnitedHealthcare
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Category
Lexette
Wynzora
At A Glance
Topical
Twice daily
Corticosteroid
Topical
Daily
Vitamin D3 analog + corticosteroid
Indications
- Psoriasis vulgaris
- Psoriasis vulgaris
Dosing
Psoriasis vulgaris Apply a thin uniform film to affected skin twice daily for up to 2 weeks; shake can and invert before use; do not exceed 50 g per week; avoid face, groin, and axillae; not for use with occlusive dressings unless directed by physician.
Psoriasis vulgaris Apply to affected areas once daily for up to 8 weeks; do not use more than 100 g per week; discontinue when control is achieved.
Contraindications
—
—
Adverse Reactions
Most common (>=1%) Application site burning/stinging, application site pain, headache
Postmarketing Folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, irritation, striae, miliaria
Most common (>=1%) Upper respiratory infection, headache, application site irritation
Postmarketing Atrophy, striae, telangiectasias, itching, dryness, hypopigmentation, perioral dermatitis, secondary infection, miliaria, cataracts, glaucoma, increased intraocular pressure
Pharmacology
Topical super-high potency corticosteroid; halobetasol propionate plays a role in cellular signaling, immune function, inflammation, and protein regulation, though its precise mechanism of action in plaque psoriasis is unknown.
WYNZORA Cream combines calcipotriene, a synthetic vitamin D3 analog, and betamethasone dipropionate, a synthetic corticosteroid; the exact mechanisms of their actions in plaque psoriasis are unknown.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Lexette
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (5/12) · Qty limit (9/12)
Wynzora
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (9/12)
UnitedHealthcare
Lexette
- Covered on 4 commercial plans
- PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
Wynzora
- Covered on 4 commercial plans
- PA (1/8) · Step Therapy (1/8) · Qty limit (0/8)
Humana
Lexette
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (2/3)
Wynzora
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (1/3) · Qty limit (0/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Lexette.
No savings programs available for Wynzora.
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LexetteView full Lexette profile
WynzoraView full Wynzora profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.