| Psoriasis vulgaris

Sorilux vs Taltz

Side-by-side clinical, coverage, and cost comparison for psoriasis vulgaris.
Deep comparison between: Sorilux vs Taltz with Prescriber.AI
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Safety signalsTaltz has a higher rate of injection site reactions vs Sorilux based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Taltz but not Sorilux, including UnitedHealthcare
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Sorilux
Taltz
At A Glance
Topical
Twice daily
Synthetic vitamin D3 analog
SC injection
Every 4 weeks (maintenance)
IL-17A antagonist
Indications
  • Psoriasis vulgaris
  • Psoriasis vulgaris
  • Arthritis, Psoriatic
  • Ankylosing spondylitis
  • Non-Radiographic Axial Spondyloarthritis
Dosing
Psoriasis vulgaris Apply a thin layer twice daily to affected areas and rub in gently and completely; avoid contact with the face and eyes.
Psoriasis vulgaris 160 mg SC at Week 0, then 80 mg at Weeks 2, 4, 6, 8, 10, 12, followed by 80 mg every 4 weeks.
Arthritis, Psoriatic 160 mg SC at Week 0, followed by 80 mg every 4 weeks.
Ankylosing spondylitis, Non-Radiographic Axial Spondyloarthritis 160 mg SC at Week 0, followed by 80 mg every 4 weeks.
Contraindications
  • Known hypercalcemia
  • Previous serious hypersensitivity reaction to ixekizumab or to any of the excipients
Adverse Reactions
Most common (>=1%) Application site erythema, application site pain
Postmarketing Application site vesicles
Most common (>=1%) Injection site reactions, upper respiratory tract infections, nausea, tinea infections.
Serious Serious infections, hypersensitivity reactions including anaphylaxis, inflammatory bowel disease.
Pharmacology
Calcipotriene is a synthetic vitamin D3 analog with similar receptor binding affinity as natural vitamin D3; the exact mechanism contributing to clinical efficacy in psoriasis is unknown.
Humanized IgG4 monoclonal antibody that selectively binds to interleukin-17A (IL-17A) and inhibits its interaction with the IL-17 receptor.
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Most Common Insurance
Anthem BCBS
Sorilux
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (6/12) · Qty limit (9/12)
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Taltz
  • Covered on 5 commercial plans
  • PA (10/12) · Step Therapy (10/12) · Qty limit (9/12)
View full coverage details ›
UnitedHealthcare
Sorilux
  • Covered on 4 commercial plans
  • PA (0/8) · Step Therapy (0/8) · Qty limit (0/8)
View full coverage details ›
Taltz
  • Covered on 4 commercial plans
  • PA (1/8) · Step Therapy (0/8) · Qty limit (1/8)
View full coverage details ›
Humana
Sorilux
  • Covered on 0 commercial plans
  • PA (1/3) · Step Therapy (2/3) · Qty limit (2/3)
View full coverage details ›
Taltz
  • Covered on 0 commercial plans
  • PA (3/3) · Step Therapy (3/3) · Qty limit (3/3)
View full coverage details ›
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Sorilux.
$25/momo
Taltz Savings Card - Non-covered benefit
Commercial or private insurance
Medicare, Medicaid, VA, TRICARE
Final cost depends on formulary coverage
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SoriluxView full Sorilux profile
TaltzView full Taltz profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.