| Psoriasis vulgaris
Ultravate vs Vtama
Side-by-side clinical, coverage, and cost comparison for psoriasis vulgaris.Deep comparison between: Ultravate vs Vtama with Prescriber.AI
AI compares prescribing info and payer-specific access barriers across 1,200+ formularies. Here's a preview of what prescribers are already asking.Safety signalsVtama has a higher rate of injection site reactions vs Ultravate based on FDA-approved prescribing information
Coverage gaps3 major payers require step therapy for Vtama but not Ultravate, including UnitedHealthcare
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Category
Ultravate
Vtama
At A Glance
Topical
Twice daily
Topical corticosteroid
Topical
Daily
AhR agonist
Indications
- Psoriasis vulgaris
- Psoriasis vulgaris
- Dermatitis, Atopic
Dosing
Psoriasis vulgaris Apply a thin layer to affected skin twice daily for up to two weeks; total dosage should not exceed 50 grams (50 ml) per week.
Psoriasis vulgaris, Dermatitis, Atopic Apply a thin layer to affected areas once daily; wash hands after application unless VTAMA cream is for treatment of the hands; not for oral, ophthalmic, or intravaginal use.
Contraindications
—
—
Adverse Reactions
Most common (>=1%) Telangiectasia, application site atrophy, headache
Less common (<1%, >0.1%) Application site discoloration, herpes zoster, influenza, nasopharyngitis, otitis media acute, throat infection, wound, increased blood pressure
Most common (>=1%) - Plaque Psoriasis Folliculitis, nasopharyngitis, contact dermatitis, headache, pruritus, influenza
Most common (>=1%) - Atopic Dermatitis Upper respiratory tract infection, folliculitis, lower respiratory tract infection, headache, asthma, vomiting, ear infection, pain in extremity, abdominal pain
Pharmacology
Halobetasol propionate is a super-high potency topical corticosteroid that plays a role in cellular signaling, immune function, inflammation, and protein regulation; the precise mechanism of action in plaque psoriasis is unknown.
Tapinarof is an aryl hydrocarbon receptor (AhR) agonist; the specific mechanisms by which VTAMA cream exerts its therapeutic actions in plaque psoriasis and atopic dermatitis are unknown.
Enter your patient's insuranceCheck specific coverage details for your patient.
Most Common Insurance
Anthem BCBS
Ultravate
- Covered on 5 commercial plans
- PA (0/12) · Step Therapy (5/12) · Qty limit (9/12)
Vtama
- Covered on 5 commercial plans
- PA (10/12) · Step Therapy (10/12) · Qty limit (9/12)
UnitedHealthcare
Ultravate
- Covered on 4 commercial plans
- PA (1/8) · Step Therapy (1/8) · Qty limit (0/8)
Vtama
- Covered on 4 commercial plans
- PA (5/8) · Step Therapy (4/8) · Qty limit (4/8)
Humana
Ultravate
- Covered on 0 commercial plans
- PA (1/3) · Step Therapy (0/3) · Qty limit (2/3)
Vtama
- Covered on 0 commercial plans
- PA (3/3) · Step Therapy (3/3) · Qty limit (3/3)
Coverage data sourced from MMIT. Updated monthly.
Savings
No savings programs available for Ultravate.
Cost estimate not availableAssistance Fund: Psoriasis
Commercial or private insurance
Medicare, Medicaid, VA, TRICARE
Final cost depends on formulary coverage
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UltravateView full Ultravate profile
Clinical data sourced from FDA-approved labeling. Coverage data via MMIT. Updated monthly.