Activase Drug Interactions: 37 Major, 183 Moderate
Activase (Alteplase) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Activase. Always confirm against the full prescribing information.
100 interactions
Aceclofenac
The risk or severity of bleeding and hemorrhage can be increased when Aceclofenac is combined with Alteplase.
Level 1 evidence
Acenocoumarol
The risk or severity of bleeding can be increased when Alteplase is combined with Acenocoumarol.
Level 2 evidence
Acetylsalicylic acid
Acetylsalicylic acid may increase the anticoagulant activities of Alteplase.
Level 1 evidence
Alogliptin
The risk or severity of angioedema can be increased when Alteplase is combined with Alogliptin.
Level 2 evidence
Alpha-1-proteinase inhibitor
The therapeutic efficacy of Alpha-1-proteinase inhibitor can be decreased when used in combination with Alteplase.
Level 2 evidence
Aminocaproic acid
The therapeutic efficacy of Aminocaproic acid can be decreased when used in combination with Alteplase.
Level 2 evidence
Aminosalicylic acid
The risk or severity of bleeding can be increased when Aminosalicylic acid is combined with Alteplase.
Level 2 evidence
Anagrelide
The risk or severity of bleeding can be increased when Anagrelide is combined with Alteplase.
Level 1 evidence
Antipyrine
The risk or severity of bleeding and hemorrhage can be increased when Antipyrine is combined with Alteplase.
Level 1 evidence
Antithrombin Alfa
The risk or severity of bleeding can be increased when Alteplase is combined with Antithrombin Alfa.
Level 2 evidence
Antithrombin III human
The risk or severity of bleeding can be increased when Alteplase is combined with Antithrombin III human.
Level 2 evidence
Argatroban
The risk or severity of bleeding can be increased when Alteplase is combined with Argatroban.
Level 2 evidence
Enter your NPI to unlock 16 major interactions for Activase
Activase (Alteplase) has 365 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Activase (Alteplase) has 37 major, 183 moderate, and 145 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Activase. Always confirm against the full prescribing information.