Allopurinol Drug Interactions: 15 Major, 379 Moderate
Allopurinol Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Allopurinol. Always confirm against the full prescribing information.
100 interactions
Abacavir
Allopurinol may increase the hepatotoxic activities of Abacavir.
Level 2 evidence
Abemaciclib
Abemaciclib may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Level 2 evidence
Abiraterone
Allopurinol may increase the hepatotoxic activities of Abiraterone.
Level 2 evidence
Acarbose
Acarbose may increase the hepatotoxic activities of Allopurinol.
Level 2 evidence
Acenocoumarol
The risk or severity of bleeding can be increased when Allopurinol is combined with Acenocoumarol.
Level 2 evidence
Acetaminophen
Acetaminophen may increase the hepatotoxic activities of Allopurinol.
Level 2 evidence
Acetazolamide
Allopurinol may increase the hepatotoxic activities of Acetazolamide.
Level 2 evidence
Acetylsalicylic acid
The therapeutic efficacy of Allopurinol can be decreased when used in combination with Acetylsalicylic acid.
Level 1 evidence
Acitretin
Allopurinol may increase the hepatotoxic activities of Acitretin.
Level 2 evidence
Acyclovir
The excretion of Allopurinol can be decreased when combined with Acyclovir.
Level 2 evidence
Afatinib
Afatinib may decrease the excretion rate of Allopurinol which could result in a higher serum level.
Level 2 evidence
Albendazole
Allopurinol may increase the hepatotoxic activities of Albendazole.
Level 2 evidence
Enter your NPI to unlock 2 major interactions for Allopurinol
Allopurinol has 950 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Allopurinol has 15 major, 379 moderate, and 556 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Allopurinol. Always confirm against the full prescribing information.