Tumor Necrosis Factor Receptor Blocking Activity

Tumor Necrosis Factor Blocker

Arthritis, Rheumatoid

Colitis, Ulcerative

Crohn Disease

Spondylitis, Ankylosing

Arthritis, Psoriatic

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Infliximab-axxq, a tumor necrosis factor (TNF) blocker, is a chimeric IgG1κ monoclonal antibody (composed of human constant and murine variable regions). It has a molecular weight of approximately 149.1 kilodaltons. Infliximab-axxq is produced in a recombinant Chinese Hamster Ovary (CHO) cell line.</p><p>AVSOLA (infliximab-axxq) for injection is supplied as a sterile, preservative-free, white to slightly yellow, lyophilized powder for intravenous infusion after reconstitution and dilution. Following reconstitution with 10 mL of Sterile Water for Injection, USP, the final concentration is 10 mg/mL and the resulting pH is approximately 7.2. Each single-dose vial contains 100 mg infliximab-axxq, dibasic sodium phosphate, anhydrous (4.9 mg), monobasic sodium phosphate, monohydrate (2.2 mg), polysorbate 80 (0.5 mg), and sucrose (500 mg).</p></section>

AVSOLA

infliximab

infliximab-axxq

infliximab-axxq 100 MG Injection

Avsola

infliximab-axxq 100 MG Injection [Avsola]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event

Prescribing Information

Medication Guide 

Submit MSL Request 

Pharmacy List 

Billing & Coding Guide 

Reimbursement Information 

Coverage Authorization Request 

Coverage Authorization Appeals

Letter of Medical Necessity 

Benefits Investigation Form 

Benefits Investigation - Online 

Amgen HCP Office Attestation Form 

Enroll in Patient Savings Program 

Other HCP Resources 

About Avsola 

Receiving Avsola 

NICA Infusion Center Locator 

Patient Brochure 

Patient Brochure - Spanish

Biosimilar Patient Flashcard

Switching From Remicade to Avsola Brochure 

Instructions For Use: Plaque Psoriasis

Instructions For Use: Psoriatic Arthritis

Instructions For Use: Ankylosing Spondylitis

Instructions For Use: Rheumatoid Arthritis

Instructions For Use: Pediatric Ulcerative Colitis

Instructions For Use: Ulcerative Colitis

Instructions For Use: Pediatric Crohn’s Disease

Instructions For Use: Crohn’s Disease