Histamine-1 Receptor Antagonist

Conjunctivitis, Allergic

<section class="Section" data-sectioncode="34089-3"><a name="i4i_description_id_94542c8b-e8fa-4f89-a45e-4f70eaa06c07"></a><a name="section-8"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">BEPREVE (bepotastine besilate ophthalmic solution) 1.5% is a sterile, topically administered drug for ophthalmic use. Each mL of  BEPREVE contains 15 mg bepotastine besilate. Bepotastine besilate is designated chemically as (+) -4-[[(S)-p-chloro-alpha -2-pyridylbenzyl]oxy]-1-piperidine butyric acid monobenzenesulfonate. The chemical structure for bepotastine besilate is:</p><div class="Figure"><a name="id425"></a><img alt="Chemical Structure" src="e8c7bd70-e024-4a70-81c9-0bf4a35e3b3c-01.jpg"/></div><p>Bepotastine besilate is a white to pale yellowish-white crystalline powder. The molecular weight of bepotastine besilate is 547.06 daltons. BEPREVE ophthalmic solution is supplied as a sterile, aqueous 1.5% solution, with an approximate pH of 6.8. The osmolality of  BEPREVE (bepotastine besilate ophthalmic solution) 1.5% is approximately 295 mOsm/kg.</p><p>Each mL of  BEPREVE (bepotastine besilate ophthalmic solution) 1.5% contains:</p><dl><dt>•</dt><dd>Active: bepotastine besilate 15 mg (equivalent to 10.7 mg bepotastine)</dd><dt>•</dt><dd>Inactives: monobasic sodium phosphate dihydrate, sodium chloride, sodium hydroxide to adjust pH, and water for injection, USP</dd><dt>•</dt><dd>Preservative: benzalkonium chloride 0.005%</dd></dl></section>

Bepreve

bepotastine besilate

bepotastine

bepotastine besilate 15 MG/ML Ophthalmic Solution

bepotastine besilate 15 MG/ML Ophthalmic Solution [Bepreve]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

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Taltz

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Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

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Stelara

Skyrizi

Ilumya

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Cluster Headache

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Emgality

Qulipta

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Ubrelvy

Nurtec ODT

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Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

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Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

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Olumiant

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Zeposia

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Entyvio

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Instructions For Use: Itching Associated With Allergic Conjunctivitis.