What is the dosage of Botox?

Botox is available in 2 dosages, including 100 unt Injection and 200 unt Injection

What is Botox mechanism of action?

Botox mechanism of action is Acetylcholine Release Inhibitors

Botox Prescribing & Dosing Schedule

Q: What does Botox treat?

Botox treats Blepharospasm, Dystonia, Fissure in Ano, Hyperhidrosis, Migraine Disorders, Muscle Rigidity, Skin Diseases, Genetic, Strabismus and Urinary Bladder, Overactive

Q: What is Botox made of?

Botox contains botulinum toxin type A which is a Acetylcholine Release Inhibitor

Q: How is Botox administered?

Botox is administered as a Injectable

Dosage & Administration

* Follow indication-specific dosage and administration recommendations.
In a 3 month interval, do not exceed a total dose of:
• Adults: 400 Units
• Pediatrics: the lesser of 10 Units/kg or 340 Units

* See Preparation and Dilution Technique for instructions on BOTOX reconstitution, storage, and preparation before injection

* Overactive Bladder: Recommended total dose 100 Units, as 0.5 mL (5 Units) injections across 20 sites into the detrusor

* Adult Detrusor Overactivity associated with a Neurologic Condition: Recommended total dose 200 Units, as 1 mL (~6.7 Units) injections across 30 sites into the detrusor

* Pediatric Detrusor Overactivity associated with a Neurologic Condition: 0.5 mL injections across 20 sites into the detrusor
• Greater than or equal to 34 kg: Recommended total dose is 200 Units
• Less than 34 kg: Recommended total dose is 6 Units/kg

* Chronic Migraine: Recommended total dose 155 Units, as 0.1 mL (5 Units) injections per each site divided across 7 head/neck muscles

* Adult Upper Limb Spasticity: Recommended total dose up to 400 Units divided among affected muscles

* Adult Lower Limb Spasticity: Recommended total dose 300 Units to 400 Units divided across ankle and toe muscles

* Pediatric Upper Limb Spasticity: Recommended total dose 3 Units/kg to 6 Units/kg (maximum 200 Units) divided among affected muscles

* Pediatric Lower Limb Spasticity: Recommended total dose 4 Units/kg to 8 Units/kg (maximum 300 Units) divided among affected muscles

* Cervical Dystonia: Base dosing on the patient’s head and neck position, localization of pain, muscle hypertrophy, patient response, and adverse event history; use lower initial dose in botulinum toxin naïve patients

* Axillary Hyperhidrosis: 50 Units per axilla

* Blepharospasm: 1.25 Units-2.5 Units into each of 3 sites per affected eye

* Strabismus: The dose is based on prism diopter correction or previous response to treatment with BOTOX

Get Your Patient on Botox

See your patient's specific prior authorization requirements including coverage restrictions and step therapies

Or select your Insurance from the list below:

Botox Prescribing Information

Contact Medical Science Liaison

Report Adverse Event

Request Botox Samples

Online Sample Form

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Botox Prior Authorization Resources

Most recent state uniform prior authorization forms

Verified: Sep 24, 2024Arizona - Uniform Prior Authorization Form

Verified: Sep 24, 2024Colorado - Uniform Prior Authorization Form

Verified: Sep 24, 2024Hawaii - Uniform Prior Authorization Form

Verified: Sep 24, 2024Illinois - Uniform Prior Authorization Form

Verified: Sep 24, 2024Indiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Louisiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Minnesota - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Hampshire - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Mexico - Uniform Prior Authorization Form

Verified: Sep 24, 2024Oregon - Uniform Prior Authorization Form

Verified: Sep 24, 2024Texas - Uniform Prior Authorization Form

Verified: Oct 05, 2024Washington - Uniform Prior Authorization Form

Verified: Oct 05, 2024Wisconsin - Uniform Prior Authorization Form

Reimbursement help (FRM)

Receive Assistance from an FRM Regarding Reimbursement Information

Botox Financial Assistance Options

Copay savings program

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form