What is the dosage of Botox?

Botox is available in 2 dosages, including 100 unt Injection and 200 unt Injection

What does Botox treat?

Botox treats Blepharospasm, Dystonia, Fissure in Ano, Hyperhidrosis, Migraine Disorders, Muscle Rigidity, Genetic Skin Diseases, Strabismus and Overactive Urinary Bladder

What is Botox made of?

Botox contains botulinum toxin type A which is a Acetylcholine Release Inhibitor

How is Botox administered?

Botox is administered as a Injectable

What is Botox mechanism of action?

Botox mechanism of action is Acetylcholine Release Inhibitors

Dosage & Administration Drug label Samples Prior authorization Financial assistance

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Botox

(botulinum toxin type A)

Botox 100 UNT InjectionBotox 200 UNT Injection

BLACK BOX WARNING

Dosage & administration

* Follow indication-specific dosage and administration recommendations.
In a 3 month interval, do not exceed a total dose of:
• Adults: 400 Units
• Pediatrics: the lesser of 10 Units/kg or 340 Units

* See Preparation and Dilution Technique for instructions on BOTOX reconstitution, storage, and preparation before injection

* Overactive Bladder: Recommended total dose 100 Units, as 0.5 mL (5 Units) injections across 20 sites into the detrusor

* Adult Detrusor Overactivity associated with a Neurologic Condition: Recommended total dose 200 Units, as 1 mL (~6.7 Units) injections across 30 sites into the detrusor

* Pediatric Detrusor Overactivity associated with a Neurologic Condition: 0.5 mL injections across 20 sites into the detrusor
• Greater than or equal to 34 kg: Recommended total dose is 200 Units
• Less than 34 kg: Recommended total dose is 6 Units/kg

* Chronic Migraine: Recommended total dose 155 Units, as 0.1 mL (5 Units) injections per each site divided across 7 head/neck muscles

* Adult Upper Limb Spasticity: Recommended total dose up to 400 Units divided among affected muscles

* Adult Lower Limb Spasticity: Recommended total dose 300 Units to 400 Units divided across ankle and toe muscles

* Pediatric Upper Limb Spasticity: Recommended total dose 3 Units/kg to 6 Units/kg (maximum 200 Units) divided among affected muscles

* Pediatric Lower Limb Spasticity: Recommended total dose 4 Units/kg to 8 Units/kg (maximum 300 Units) divided among affected muscles

* Cervical Dystonia: Base dosing on the patient’s head and neck position, localization of pain, muscle hypertrophy, patient response, and adverse event history; use lower initial dose in botulinum toxin naïve patients

* Axillary Hyperhidrosis: 50 Units per axilla

* Blepharospasm: 1.25 Units-2.5 Units into each of 3 sites per affected eye

* Strabismus: The dose is based on prism diopter correction or previous response to treatment with BOTOX

drug label

Botox prescribing information

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samples

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prior authorization

Botox prior authorization resources

Most recent Botox prior authorization forms

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Verified: Sep 04, 2023Highmark BCBS Northeastern NY - Outpatient Botulinum Toxin Prior Authorization Form (Medical Benefit)

Verified: Sep 04, 2023Highmark BCBS Western NY - Outpatient Botulinum Toxin Prior Authorization Form (Medical Benefit)

Verified: Sep 03, 2023Highmark BCBS West Virginia - Outpatient Botulinum Toxin Prior Authorization Form (Medical Benefit)

Verified: Sep 03, 2023Highmark BCBS Delaware - Outpatient Botulinum Toxin Prior Authorization Form (Medical Benefit)

Verified: Sep 03, 2023Highmark BCBS Central PA - Outpatient Botulinum Toxin Prior Authorization Form (Medical Benefit)

Verified: Sep 02, 2023Highmark BCBS Western PA - Outpatient Botulinum Toxin Prior Authorization Form (Medical Benefit)

Verified: Oct 02, 2023Blue Cross Blue Shield of Michigan - FEP Botox Prior Authorization Form (Medical Benefit)

Verified: Sep 27, 2023Cigna - Botox Prior Authorization Form

Verified: Sep 26, 2023Blue Cross Blue Shield of Michigan - Botulinum Prior Authorization Form (Medical Benefit)

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Reimbursement help (FRM)

Receive Assistance from an FRM Regarding Reimbursement Information

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financial assistance

Botox financial assistance options

Co-pay savings program

commercial only

Enroll in Patient Savings Program

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Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form