Chlorthalidone Drug Interactions: 8 Major, 282 Moderate
Chlorthalidone Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Chlorthalidone. Always confirm against the full prescribing information.
100 interactions
Acarbose
The therapeutic efficacy of Acarbose can be decreased when used in combination with Chlorthalidone.
Level 2 evidence
Aceclofenac
The therapeutic efficacy of Chlorthalidone can be decreased when used in combination with Aceclofenac.
Level 2 evidence
Acetylsalicylic acid
Acetylsalicylic acid may decrease the excretion rate of Chlorthalidone which could result in a higher serum level.
Level 1 evidence
Alfentanil
The therapeutic efficacy of Chlorthalidone can be decreased when used in combination with Alfentanil.
Level 2 evidence
Allopurinol
The risk of a hypersensitivity reaction to Allopurinol is increased when it is combined with Chlorthalidone.
Level 1 evidence
Alogliptin
The therapeutic efficacy of Alogliptin can be decreased when used in combination with Chlorthalidone.
Level 2 evidence
Amobarbital
The risk or severity of hypotension and orthostatic hypotension can be increased when Amobarbital is combined with Chlorthalidone.
Level 2 evidence
Antipyrine
The therapeutic efficacy of Chlorthalidone can be decreased when used in combination with Antipyrine.
Level 2 evidence
Aripiprazole
The risk or severity of hypotension can be increased when Aripiprazole is combined with Chlorthalidone.
Level 1 evidence
Aripiprazole lauroxil
The risk or severity of hypotension can be increased when Aripiprazole lauroxil is combined with Chlorthalidone.
Level 1 evidence
Baclofen
The risk or severity of adverse effects can be increased when Baclofen is combined with Chlorthalidone.
Level 1 evidence
Balsalazide
The therapeutic efficacy of Chlorthalidone can be decreased when used in combination with Balsalazide.
Level 2 evidence
Enter your NPI to unlock 1 major interaction for Chlorthalidone
Chlorthalidone has 820 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Chlorthalidone has 8 major, 282 moderate, and 530 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Chlorthalidone. Always confirm against the full prescribing information.