Leukemia, Lymphocytic, Chronic, B-Cell

<section class="Section" data-sectioncode="34089-3"><a name="ID95"></a><a name="section-9"></a><p></p><h1>11 DESCRIPTION</h1><p class="First"><a name="ID96"></a>COPIKTRA (duvelisib) is a kinase inhibitor.</p><p>Duvelisib is a white-to-off-white crystalline solid with the empirical formula C<span class="Sub">22</span>H<span class="Sub">17</span>ClN<span class="Sub">6</span>O•H<span class="Sub">2</span>O and a molecular weight of 434.88 g/mol.  Hydration can vary with relative humidity.  Duvelisib contains a single chiral center as (<span class="Italics">S</span>) enantiomer.  Duvelisib is soluble in ethanol and practically insoluble in water.  Duvelisib is described chemically as a hydrate of (S)-3-(1-(9H-purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one and has the following chemical structure:</p><div class="Figure"><img alt="Image" src="e7c8f6bf-6c16-4a6e-93c8-e7241b160aa8-01.jpg"/></div><p><a name="ID98"></a>COPIKTRA capsules are for oral administration and are supplied as white to off-white opaque and Swedish orange opaque capsules (25 mg, on anhydrous basis) or pink opaque capsules (15 mg, on anhydrous basis), and contain the following inactive ingredients: colloidal silicon dioxide, crospovidone, magnesium stearate, and microcrystalline cellulose.  Capsule shells contain gelatin, titanium dioxide, black ink, and red iron oxide. </p></section>

COPIKTRA

duvelisib

duvelisib 15 MG Oral Capsule

Copiktra

duvelisib 15 MG Oral Capsule [Copiktra]

duvelisib 25 MG Oral Capsule

duvelisib 25 MG Oral Capsule [Copiktra]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information

Medication Guide 

Submit MSL Request 

Pharmacy List 

Secura Care Enrollment Form 

Coverage Authorization Request 

Coverage Authorization Appeals 

Secura Bio Quick Start Program - Bridge Program

Enroll in Patient Savings Program 

Other HCP Resources

Patient Wallet Card 

About Copiktra 

Taking Copiktra 

Side Effects 

Patient Resources

Secura Care Patient Support Program Brochure 

Instructions For Use: CLL/SLL