Daptomycin Drug Interactions: 3 Major, 323 Moderate
Daptomycin Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Daptomycin. Always confirm against the full prescribing information.
100 interactions
Abemaciclib
The serum concentration of Abemaciclib can be increased when it is combined with Daptomycin.
Level 2 evidence
Abrocitinib
The serum concentration of Daptomycin can be increased when it is combined with Abrocitinib.
Level 2 evidence
Acenocoumarol
The risk or severity of bleeding can be increased when Daptomycin is combined with Acenocoumarol.
Level 2 evidence
Adagrasib
The serum concentration of Daptomycin can be increased when it is combined with Adagrasib.
Level 2 evidence
Afatinib
The serum concentration of Daptomycin can be increased when it is combined with Afatinib.
Level 2 evidence
Alendronic acid
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Daptomycin is combined with Alendronic acid.
Level 2 evidence
Ambrisentan
The serum concentration of Ambrisentan can be increased when it is combined with Daptomycin.
Level 2 evidence
Amikacin
Daptomycin may decrease the excretion rate of Amikacin which could result in a higher serum level.
Level 2 evidence
Amiodarone
The serum concentration of Daptomycin can be increased when it is combined with Amiodarone.
Level 2 evidence
Amphotericin B
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Daptomycin is combined with Amphotericin B.
Level 2 evidence
Apalutamide
The serum concentration of Daptomycin can be decreased when it is combined with Apalutamide.
Level 1 evidence
Apixaban
The serum concentration of Apixaban can be increased when it is combined with Daptomycin.
Daptomycin has 967 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Daptomycin has 3 major, 323 moderate, and 641 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Daptomycin. Always confirm against the full prescribing information.