Donepezil Hydrochloride Drug Interactions: 69 Major
Donepezil Hydrochloride Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Donepezil Hydrochloride. Always confirm against the full prescribing information.
100 interactions
Abacavir
The risk or severity of liver damage can be increased when Donepezil is combined with Abacavir.
Level 2 evidence
Abatacept
The metabolism of Donepezil can be increased when combined with Abatacept.
Level 1 evidence
Abemaciclib
Abemaciclib may decrease the excretion rate of Donepezil which could result in a higher serum level.
Level 2 evidence
Abiraterone
The metabolism of Donepezil can be decreased when combined with Abiraterone.
Level 1 evidence
Acalabrutinib
The risk or severity of liver damage can be increased when Donepezil is combined with Acalabrutinib.
Level 2 evidence
Acamprosate
The risk or severity of liver damage can be increased when Acamprosate is combined with Donepezil.
Level 2 evidence
Acarbose
The risk or severity of liver damage can be increased when Acarbose is combined with Donepezil.
Level 2 evidence
Acebutolol
Donepezil may increase the bradycardic activities of Acebutolol.
Level 2 evidence
Aceclidine
The risk or severity of adverse effects can be increased when Donepezil is combined with Aceclidine.
Level 1 evidence
Aceclofenac
The risk or severity of liver damage can be increased when Donepezil is combined with Aceclofenac.
Level 2 evidence
Acetaminophen
The risk or severity of liver damage can be increased when Acetaminophen is combined with Donepezil.
Level 2 evidence
Acetazolamide
The risk or severity of CNS depression can be increased when Acetazolamide is combined with Donepezil.
Level 2 evidence
Enter your NPI to unlock 4 major interactions for Donepezil Hydrochloride
Donepezil Hydrochloride has 1153 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Donepezil Hydrochloride has 69 major, 988 moderate, and 96 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Donepezil Hydrochloride. Always confirm against the full prescribing information.