Duloxetine Drug Interactions: 36 Major, 585 Moderate
Duloxetine (Duloxetine Hydrochloride) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Duloxetine. Always confirm against the full prescribing information.
100 interactions
Abacavir
Duloxetine may increase the hepatotoxic activities of Abacavir.
Level 2 evidence
Abatacept
The metabolism of Duloxetine can be increased when combined with Abatacept.
Level 1 evidence
Abiraterone
The metabolism of Duloxetine can be decreased when combined with Abiraterone.
Level 1 evidence
Acarbose
The risk or severity of hypoglycemia can be increased when Duloxetine is combined with Acarbose.
Level 2 evidence
Acenocoumarol
The risk or severity of hemorrhage can be increased when Duloxetine is combined with Acenocoumarol.
Level 1 evidence
Acetaminophen
The metabolism of Acetaminophen can be decreased when combined with Duloxetine.
Level 1 evidence
Acetazolamide
The risk or severity of adverse effects can be increased when Acetazolamide is combined with Duloxetine.
Level 2 evidence
Acetylsalicylic acid
Duloxetine may increase the antiplatelet activities of Acetylsalicylic acid.
Level 1 evidence
Acitretin
Acitretin may increase the hepatotoxic activities of Duloxetine.
Level 2 evidence
Acoramidis
The metabolism of Duloxetine can be decreased when combined with Acoramidis.
Level 2 evidence
Adagrasib
The metabolism of Duloxetine can be decreased when combined with Adagrasib.
Level 2 evidence
Adalimumab
The metabolism of Duloxetine can be increased when combined with Adalimumab.
Level 1 evidence
Enter your NPI to unlock 2 major interactions for Duloxetine
Duloxetine (Duloxetine Hydrochloride) has 1175 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Duloxetine (Duloxetine Hydrochloride) has 36 major, 585 moderate, and 554 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Duloxetine. Always confirm against the full prescribing information.