Acetylcholine Release Inhibitors

Acetylcholine Release Inhibitor

Neuromuscular Blocker

Blepharospasm

Dystonia

Fissure in Ano

Hyperhidrosis

Muscle Rigidity

Skin Diseases, Genetic

Strabismus

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Botulinum toxin type A, the active ingredient in DYSPORT, is a purified neurotoxin type A complex produced by fermentation of the bacterium   <span class="Italics">Clostridium botulinum</span>type A, Hall Strain. It is purified from the culture supernatant by a series of precipitation, dialysis, and chromatography steps. The neurotoxin complex is composed of the neurotoxin, hemagglutinin proteins and non-toxin non-hemagglutinin protein. </p><p>DYSPORT® (abobotulinumtoxinA) for injection is a sterile, lyophilized powder supplied in a single-dose vial for reconstitution intended for intramuscular injection. Each vial contains 300 Units or 500 Units of lyophilized abobotulinumtoxinA, human serum albumin (125 mcg) and lactose (2.5 mg). DYSPORT   <span class="Bold"> </span>may contain trace amounts of cow's milk proteins [   <span class="Italics">see     <a href="#S4">Contraindications (4)</a> and     <a href="#S5.3">Warnings and Precautions (5.3)</a>].                       </span>]. </p><p>The primary release procedure for DYSPORT uses a cell-based potency assay to determine the potency relative to a reference standard.  The assay and reference material are specific to DYSPORT. One unit of DYSPORT corresponds to the calculated median lethal intraperitoneal dose (LD   <span class="Sub">50</span>) in mice.  Due to specific details of the assay system, such as vehicle, dilution scheme and laboratory protocols, Units of biological activity of DYSPORT cannot be converted into Units of any other botulinum toxin or any toxin assessed with any other specific assay method. </p></section>

Dysport

botulinum toxin type A

abobotulinumtoxinA 300 UNT Injection

abobotulinumtoxinA 300 UNT Injection [Dysport]

abobotulinumtoxinA

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event

Prescribing Information

Medication Guide 

Pharmacy List 

How To Order Dysport

Reimbursement Guide 

Coverage Authorization Request

Coverage Authorization Appeals

Ipsen Cares Enrollment Form 

Ipsen Cares Enrollment Form - Online

Ipsen Care Patient Assistance Program 

Enroll in Patient Savings Program

Letter of Medical Necessity 

Med D Tier Exception

Other HCP Resources 

Doctor Discussion Guide 

About Dysport: Adult Spasticity 

Patient Resources: Adult Spasticity

About Dysport: Cervical Dystonia

Patient Resources: Cervical Dystonia

About Dysport: Pediatric Spasticity

Patient Resources: Pediatric Spasticity

Instructions For Use: Cervical Dystonia

Instructions For Use: Adult Spasticity

Instructions For Use: Pediatric Spasticity