Uric Acid-specific Enzyme

Tumor Lysis Syndrome

Hyperuricemia

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Elitek (rasburicase) is a recombinant urate-oxidase produced by a genetically modified <span class="Italics">Saccharomyces cerevisiae </span>strain. The cDNA coding for rasburicase was cloned from a strain of <span class="Italics">Aspergillus flavus.</span></p><p>Rasburicase is a tetrameric protein with identical subunits. Each subunit is made up of a single 301 amino acid polypeptide chain with a molecular mass of about 34 kDa. The drug product is a sterile, white to off-white, lyophilized powder intended for intravenous administration following reconstitution with a diluent. Elitek is supplied in 2 mL or 3 mL and 10 mL colorless, glass vials containing rasburicase at a concentration of 1.5 mg/mL after reconstitution.</p><p>Elitek 1.5 mg presentation contains 1.5 mg rasburicase, 10.6 mg mannitol, 15.9 mg L-alanine, between 12.6 and 14.3 mg of dibasic sodium phosphate (lyophilized powder), and a diluent (1 mL Water for Injection, USP, and 1 mg Poloxamer 188).</p><p>Elitek 7.5 mg presentation contains 7.5 mg of rasburicase, 53 mg mannitol, 79.5 mg L-alanine, and between 63 and 71.5 mg dibasic sodium phosphate (lyophilized powder) and a diluent (5 mL Water for Injection, USP, and 5 mg Poloxamer 188).</p></section>

Elitek

rasburicase 1.5 MG Injection

rasburicase 1.5 MG Injection [Elitek]

rasburicase 7.5 MG Injection

rasburicase 7.5 MG Injection [Elitek]

rasburicase

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

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Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

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Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

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Prurigo Nodularis

Dupixent

Opzelura

Adbry

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Xalkori

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Xeljanz

Uveitis

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Orencia

COVID-19 Treatment

Alopecia Areata

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Entyvio

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CareAssist Enrollment Form 

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Other HCP Resources - Access 

CareAssist Patient Support Program Overview

CareAssist Patient Support Program Overview - Spanish 

CareAssist Resource Navigation Flashcard 

Other HCP Resources 

Instructions For Use: Management of Plasma Uric Acid Levels In Patients with Leukemia, Lymphoma, and Solid Tumor Malignancies

Reimbursement Request (For Out of Pocket Claims) 