Epclusa Drug Interactions: 117 Major, 647 Moderate
Epclusa (Velpatasvir And Sofosbuvir) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Epclusa. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Velpatasvir can be increased when combined with Abatacept.
Level 1 evidence
Abemaciclib
Abemaciclib may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Level 2 evidence
Abiraterone
The metabolism of Velpatasvir can be decreased when combined with Abiraterone.
Level 2 evidence
Abrocitinib
The serum concentration of Velpatasvir can be increased when it is combined with Abrocitinib.
Level 2 evidence
Abrocitinib
The serum concentration of Sofosbuvir can be increased when it is combined with Abrocitinib.
Level 2 evidence
Adagrasib
The serum concentration of Velpatasvir can be increased when it is combined with Adagrasib.
Level 2 evidence
Adagrasib
The serum concentration of Sofosbuvir can be increased when it is combined with Adagrasib.
Level 2 evidence
Adalimumab
The metabolism of Velpatasvir can be increased when combined with Adalimumab.
Level 1 evidence
Adenovirus type 7 vaccine live
The therapeutic efficacy of Adenovirus type 7 vaccine live can be decreased when used in combination with Sofosbuvir.
Level 2 evidence
Adenovirus type 7 vaccine live
The therapeutic efficacy of Adenovirus type 7 vaccine live can be decreased when used in combination with Velpatasvir.
Level 2 evidence
Afatinib
The serum concentration of Afatinib can be increased when it is combined with Velpatasvir.
Level 2 evidence
Afatinib
Afatinib may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
Level 2 evidence
Enter your NPI to unlock 7 major interactions for Epclusa
Epclusa (Velpatasvir And Sofosbuvir) has 1249 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Epclusa (Velpatasvir And Sofosbuvir) has 117 major, 647 moderate, and 485 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Epclusa. Always confirm against the full prescribing information.