Esbriet Drug Interactions: 240 Major, 409 Moderate
Esbriet (Pirfenidone) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Esbriet. Always confirm against the full prescribing information.
100 interactions
Abacavir
Abacavir may increase the hepatotoxic activities of Pirfenidone.
Level 2 evidence
Abatacept
The metabolism of Pirfenidone can be increased when combined with Abatacept.
Level 1 evidence
Abrocitinib
The metabolism of Abrocitinib can be decreased when combined with Pirfenidone.
Level 2 evidence
Acarbose
Acarbose may increase the hepatotoxic activities of Pirfenidone.
Level 2 evidence
Acebutolol
The metabolism of Pirfenidone can be decreased when combined with Acebutolol.
Level 2 evidence
Acenocoumarol
The metabolism of Pirfenidone can be decreased when combined with Acenocoumarol.
Level 2 evidence
Acetaminophen
Pirfenidone may increase the hepatotoxic activities of Acetaminophen.
Level 1 evidence
Acetazolamide
Acetazolamide may increase the hepatotoxic activities of Pirfenidone.
Level 2 evidence
Acitretin
Acitretin may increase the hepatotoxic activities of Pirfenidone.
Level 2 evidence
Acoramidis
The metabolism of Pirfenidone can be decreased when combined with Acoramidis.
Level 2 evidence
Acyclovir
The metabolism of Pirfenidone can be decreased when combined with Acyclovir.
Level 2 evidence
Adagrasib
The metabolism of Pirfenidone can be decreased when combined with Adagrasib.
Level 2 evidence
Enter your NPI to unlock 25 major interactions for Esbriet
Esbriet (Pirfenidone) has 922 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Esbriet (Pirfenidone) has 240 major, 409 moderate, and 273 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Esbriet. Always confirm against the full prescribing information.