Foundayo (orforglipron) – Coverage & PA for Prescribers
Get your patient on Foundayo (Orforglipron)
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of the top 10 commercial plans cover Foundayoof the top 10 commercial health plans cover Foundayo
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of plans require PAof plans require prior authorization
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See how Foundayo stacks up on access, cost, and PA burden — the factors that affect whether your patient can actually get on therapy.
Access Metric
FoundayoOrforglipron
zepbound
mounjaro
wegovy
ozempic
Plan Coverage% of commercial plans
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PA Required% of plans requiring PA
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Copay w/ SavingsWith manufacturer card
Not available
Savings ProgramsTotal available
Not available
Approved IndicationsFDA-approved uses
Type 2 Diabetes
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Get better comparisons with Prescriber.AISee which alternative has the best coverage, lowest PA burden, and best savings for your patient's specific insurance.
Prior Authorization Resource Guide (US-OFG-2695)Comprehensive guide for HCPs submitting PA requests. Includes ICD-10 codes, BMI documentation, lifestyle modification requirements, and reauthorization tips.Updated Apr 06, 2026
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Letter of Medical Necessity Template Guide (US-OFG-2696)Template and considerations for composing LON for PA appeals. Includes sample letters, required patient information, clinical rationale guidance, and plan submission requirements.Updated Apr 06, 2026
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Prescribing Information
Indications
FOUNDAYO TM is indicated in combination with a reduced-calorie diet and increased physical activity to reduce excess body weight and maintain weight reduction long term in adults with obesity or adults with overweight in the presence of at least one weight-related comorbid condition.
Limitations of Use
Concomitant use with another GLP-1 receptor agonist is not recommended.
Dosing Titration
0.8
0.8 mgFirst 4 weeksTitration
2.5
2.5 mg≥4 weeks laterEscalation
5.5
5.5 mg≥4 weeks laterEscalation
9
9 mg≥4 weeks laterEscalation
14.5
14.5 mg≥4 weeks laterEscalation
17.2
17.2 mg≥4 weeks laterMax dose
0.8
0.8 mgFirst 4 weeksTitration
2.5
2.5 mg≥4 weeks laterEscalation
5.5
5.5 mg≥4 weeks laterEscalation
9
9 mg≥4 weeks laterEscalation
14.5
14.5 mg≥4 weeks laterEscalation
17.2
17.2 mg≥4 weeks laterMax dose
Common Side Effects
Nausea
35%
Diarrhea
25%
Constipation
24%
Vomiting
24%
Abdominal pain
14%
Contraindications
A personal or family history of MTC or in patients with MEN 2.
Known serious hypersensitivity to orforglipron or any of the excipients in FOUNDAYO. Serious hypersensitivity reactions, including anaphylaxis and angioedema, have been reported with GLP-1 receptor agonists.
Full FDA Prescribing Information
Access the complete FDA-approved prescribing label for Foundayo, including approved indications, recommended dosage & administration schedules, contraindications, warnings & precautions, adverse reactions, drug interactions, and use in specific populations.View full prescribing information
Check medication interactionsMay interact with insulin and sulfonylureas (increased hypoglycemia risk). May affect absorption of oral medications due to delayed gastric emptying. Monitor patients closely when initiating or adjusting concomitant oral medications.
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Resources
Patient Education Materials4
Dosing & Administration Guides2
Clinical Information1
Insurance Resources2
Dosage & administration
DOSAGE AND ADMINISTRATION
Take FOUNDAYO orally once daily, with or without food. (2.1 )
Swallow tablets whole. Do not break, crush, or chew. (2.1 )
Starting dosage is 0.8 mg once daily. After at least 30 days, increase dosage to 2.5 mg once daily. (2.1 )
After at least 30 days on the 2.5 mg dosage, increase dosage to 5.5 mg once daily. (2.1 )
Dosage may be increased to the next dosage level (9 mg, 14.5 mg, or 17.2 mg once daily) after at least 30 days on the current dosage, based on treatment response and tolerability. (2.1 )
Take FOUNDAYO orally once daily, with or without food.
Swallow tablets whole. Do not break, crush, or chew.
Do not take more than one tablet per day.
Recommended Dosage Escalation
Follow the FOUNDAYO starting dosage and escalation described below to reduce the risk of gastrointestinal (GI) adverse reactions [see Warnings and Precautions (5.3 ), Adverse Reactions (6 )] .
The starting dosage is 0.8 mg orally once daily. After at least 30 days on the 0.8 mg dosage, increase the dosage to 2.5 mg once daily.
After at least 30 days on the 2.5 mg dosage, increase the dosage to 5.5 mg once daily.
The dosage may be increased to the next dosage level (9 mg, 14.5 mg, or 17.2 mg once daily) after at least 30 days on the current dosage, based on treatment response and tolerability.
The maximum dosage of FOUNDAYO is 17.2 mg once daily.
Dosage Modification for Concomitant Use with CYP3A4 Inhibitors and CYP3A4 Inducers
FOUNDAYO dosage modification may be required to manage interactions with some concomitant medications [see Drug Interactions (7.1 ), Clinical Pharmacology (12.3 )] .
Strong CYP3A4 Inhibitors
Avoid strong CYP3A4 inhibitors that also inhibit OATP1B when taking FOUNDAYO.
The maximum dosage of FOUNDAYO is 9 mg once daily when used concomitantly with a strong CYP3A4 inhibitor [see Drug Interactions (7.1 ), Clinical Pharmacology (12.3 )] .
Strong and Moderate CYP3A4 Inducers
Avoid strong CYP3A4 inducers when taking FOUNDAYO.
Monitor FOUNDAYO effectiveness when concomitantly using moderate CYP3A4 inducers and escalate FOUNDAYO dosage as needed [see Dosage and Administration (2.1 , 2.3 ), Drug Interactions (7.1 ), Clinical Pharmacology (12.3 )] .
Recommendations Regarding Missed Dose
If a dose is missed, instruct patients to take the dose as soon as possible.
Advise patients not to double up the next dose.
If 7 or more consecutive doses are missed, reinitiate dosage escalation at a lower dosage to reduce the risk of gastrointestinal adverse reactions [see Dosage and Administration (2.1 ), Warnings and Precautions (5.3 ), Adverse Reactions (6 )] .
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Frequently Asked Questions
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