Fabry Disease

<section class="Section" data-sectioncode="34089-3"><a name="s_1100"></a><a name="section-8"></a><h1>11 DESCRIPTION</h1>Migalastat, an alpha-galactosidase A (alpha-Gal A) pharmacological chaperone, is a low molecular weight iminosugar and an analogue of the terminal galactose of globotriaosylceramide (GL-3).Migalastat is present in the form of a hydrochloride salt in GALAFOLD. The chemical name for migalastat hydrochloride is (+)-(2R,3S,4R,5S)-2-(hydroxymethyl) piperidine-3,4,5-triol hydrochloride. Its molecular formula is C6H13NO4•HCl, molecular mass is 199.63 g/mol, and its chemical structure is depicted below.<img alt="Chemical Structure" src="galafold-01.jpg"/>Migalastat hydrochloride is a white to almost white crystalline solid. It is freely soluble in aqueous media within the pH range of 1.2 to 7.5.GALAFOLD (migalastat) capsules for oral administration contain 123 mg of migalastat (equivalent to 150 mg migalastat hydrochloride) as a white to pale brown powder and are supplied in a size “2” hard gelatin capsule with an opaque blue cap and an opaque white body imprinted with “A1001” in black ink. The inactive ingredients are magnesium stearate and pregelatinized starch. Capsule shells consist of gelatin, indigotine - FD&amp;C Blue 2, and titanium dioxide. The black ink consists of black iron oxide, potassium hydroxide, and shellac.</section>

Galafold

migalastat

migalastat 123 MG Oral Capsule

migalastat 123 MG Oral Capsule [Galafold]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information 

Medication Guide 

Pharmacy List 

Coverage Authorization Request 

Coverage Authorization Appeals 

Galafold Referral Form 

Enroll in Patient Savings Program 

Other HCP Resources 

About Galafold 

Galafold App Download 

Taking Galafold

Patient Stories 

Patient Resources 

Fabry Self-Advocay Guide

Fabry Self-Advocacy Guide - Spanish

Fabry Variability Brochure 

Fabry Variability Brochure - Spanish

Women & Fabry Brochure 

Women & Fabry Brochure - Spanish

Fabry Side Effects Tracker 

Fabry Side Effects Tracker - Spanish

My Fabry Tracker 

My Fabry Tracker - Spanish

Instructions For Use: Fabry's Disease 