Cytochrome P450 3A Inhibitors

Kinase Inhibitor

Kinase Inhibitors

Breast Neoplasms

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">IBRANCE tablets for oral administration contain 125 mg, 100 mg, or 75 mg of palbociclib, a kinase inhibitor. The molecular formula for palbociclib is C<span class="Sub">24</span>H<span class="Sub">29</span>N<span class="Sub">7</span>O<span class="Sub">2</span>. The molecular weight is 447.54 daltons. The chemical name is 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-<span class="Italics">d</span>]pyrimidin-7(8<span class="Italics">H</span>)-one, and its structural formula is: </p><div class="Figure"><img alt="Chemical Structure" src="ibrance-01.jpg"/></div><p>Palbociclib is a yellow to orange powder. At or below pH 4, palbociclib behaves as a high-solubility compound. Above pH 4, the solubility of the drug substance reduces significantly.</p><p><span class="Italics">Inactive Ingredients:</span> Microcrystalline cellulose, colloidal silicon dioxide, crospovidone, magnesium stearate, succinic acid, HPMC 2910/hypromellose, titanium dioxide, triacetin, and FD&amp;C Blue #2/Indigo Carmine Aluminum Lake. In addition, the 75 mg and 125 mg tablets contain red iron oxide and the 100 mg tablets contain yellow iron oxide. </p></section>

Ibrance

palbociclib

palbociclib 100 MG Oral Tablet

palbociclib 100 MG Oral Tablet [Ibrance]

palbociclib 125 MG Oral Tablet

palbociclib 125 MG Oral Tablet [Ibrance]

palbociclib 75 MG Oral Tablet

palbociclib 75 MG Oral Tablet [Ibrance]

Michigan Medicine Specialty Pharmacy

Actemra

Afinitor

Alecensa

Alunbrig

Aranesp

Benlysta

Bosulif

Cabometyx

Calquence

Cometriq

Cosentyx

Cotellic

Enbrel

Erivedge

Erleada

Esbriet

Farydak

Firazyr

Gilotrif

Hycamtin

Idhifa

Imbruvica

Inlyta

Inrebic

Iressa

Jakafi

Lenvima

Lorbrena

Lynparza

Lonsurf

Matulane

Mekinist

Mektovi

Nexavar

Odomzo

Olumiant

Orlissa

Piqray

Pomalyst

Promacta

Revlimid

Rubraca

Stelara

Stivarga

Sutent

Tafinlar

Tagrisso

Talzenna

Tarceva

Tagretin

Tavalisse

Temodar

Tibsovo

Tykerb

Venclexta

Verzenio

Votrient

Xalkori

Xospata

Xtandi

Zejula

Zelboraf

Zydelig

Zykadia

Ibrance | Michigan Medicine Specialty Pharmacy | limited distribution

Does Ibrance have a limited distribution partnership with Michigan Medicine Specialty Pharmacy?

Which health plans does Michigan Medicine Specialty Pharmacy have contracts with?

Does Michigan Medicine Specialty Pharmacy work closely with Ibrance and Pfizer Laboratories Div Pfizer Inc?

Does Michigan Medicine Specialty Pharmacy offer services for Ibrance patients?

What conditions does Michigan Medicine Specialty Pharmacy support?

How does Michigan Medicine Specialty Pharmacy help with insurance?