Cytochrome P450 3A Inhibitors

Kinase Inhibitor

Kinase Inhibitors

Breast Neoplasms

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">IBRANCE tablets for oral administration contain 125 mg, 100 mg, or 75 mg of palbociclib, a kinase inhibitor. The molecular formula for palbociclib is C<span class="Sub">24</span>H<span class="Sub">29</span>N<span class="Sub">7</span>O<span class="Sub">2</span>. The molecular weight is 447.54 daltons. The chemical name is 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-<span class="Italics">d</span>]pyrimidin-7(8<span class="Italics">H</span>)-one, and its structural formula is: </p><div class="Figure"><img alt="Chemical Structure" src="ibrance-01.jpg"/></div><p>Palbociclib is a yellow to orange powder. At or below pH 4, palbociclib behaves as a high-solubility compound. Above pH 4, the solubility of the drug substance reduces significantly.</p><p><span class="Italics">Inactive Ingredients:</span> Microcrystalline cellulose, colloidal silicon dioxide, crospovidone, magnesium stearate, succinic acid, HPMC 2910/hypromellose, titanium dioxide, triacetin, and FD&amp;C Blue #2/Indigo Carmine Aluminum Lake. In addition, the 75 mg and 125 mg tablets contain red iron oxide and the 100 mg tablets contain yellow iron oxide. </p></section>

Ibrance

palbociclib

palbociclib 100 MG Oral Tablet

palbociclib 100 MG Oral Tablet [Ibrance]

palbociclib 125 MG Oral Tablet

palbociclib 125 MG Oral Tablet [Ibrance]

palbociclib 75 MG Oral Tablet

palbociclib 75 MG Oral Tablet [Ibrance]

Southern Cancer Center Pharmacy

Ibrance | Southern Cancer Center Pharmacy

Does Southern Cancer Center Pharmacy work closely with Ibrance and Pfizer Laboratories Div Pfizer Inc?

Does Southern Cancer Center Pharmacy offer services for Ibrance patients?

What conditions does Southern Cancer Center Pharmacy support?