Interleukin 1 Receptor Antagonists

Interleukin-1 Receptor Antagonist

Arthritis, Rheumatoid

Cryopyrin-Associated Periodic Syndromes

<section class="Section" data-sectioncode="34089-3"><a name="s62"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">KINERET (anakinra) is a recombinant, nonglycosylated form of the human interleukin-1 receptor antagonist (IL-1Ra). KINERET differs from native human IL-1Ra in that it has the addition of a single methionine residue at its amino terminus. KINERET consists of 153 amino acids and has a molecular weight of 17.3 kilodaltons. It is produced by recombinant DNA technology using an <span class="Italics">E coli</span> bacterial expression system.</p><p>KINERET is supplied in single use prefilled glass syringes with 29 gauge needles as a sterile, clear, colorless-to-white, preservative free solution for daily subcutaneous (SC) administration. The solution may contain trace amounts of small, translucent-to-white amorphous proteinaceous particles. Each prefilled glass syringe contains: 0.67 mL (100 mg) of anakinra in a solution (pH 6.5) containing anhydrous citric acid (1.29 mg), disodium EDTA (0.12 mg), polysorbate 80 (0.70 mg), and sodium chloride (5.48 mg) in Water for Injection, USP.</p><p>The prefilled syringe contains an outer rigid plastic needle shield attached to an inner needle cover. The syringe or needle shield components are not made with natural rubber latex.</p></section>

Kineret

anakinra

0.67 ML anakinra 149 MG/ML Prefilled Syringe

0.67 ML anakinra 149 MG/ML Prefilled Syringe [Kineret]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information

Prescribing Information - Spanish

Medication Guide 

Submit MSL Request 

Pharmacy List 

Coverage Authorization Request 

Coverage Authorization Appeals 

Enroll in Patient Savings Program 

Patient Assistance Program Application

Kineret On Track Enrollment & Prescription Form 

Other HCP Resources 

Treatment Guide 

Injection Tracker Journal

About Kineret: NOMID

Patient Stories: NOMID

Taking Kineret: NOMID

Kineret On Track Support Program 

About Kineret: Rheumatoid Arthritis 

Patient Stories: Rheumatoid Arthritis

Taking Kineret: Rheumatoid Arthritis

About Kineret: DIRA

Taking Kinaret: DIRA

Instructions For Use: Rheumatoid Arthritis 

Instructions For Use: Neonatal-Onset Multisystem Inflammatory Disease (NOMID)

Instructions For Use: Deficiency of Interleukin-1 Receptor Antagonist (DIRA)