Koselugo Drug Interactions: 133 Major, 495 Moderate
Koselugo (Selumetinib) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Koselugo. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Selumetinib can be increased when combined with Abatacept.
Level 1 evidence
Abemaciclib
Abemaciclib may decrease the excretion rate of Selumetinib which could result in a higher serum level.
Level 2 evidence
Abrocitinib
The serum concentration of Selumetinib can be increased when it is combined with Abrocitinib.
Level 2 evidence
Acenocoumarol
The metabolism of Selumetinib can be decreased when combined with Acenocoumarol.
Level 2 evidence
Acetaminophen
Selumetinib may increase the hepatotoxic activities of Acetaminophen.
Level 1 evidence
Acoramidis
The metabolism of Selumetinib can be decreased when combined with Acoramidis.
Level 2 evidence
Acyclovir
The metabolism of Selumetinib can be decreased when combined with Acyclovir.
Level 2 evidence
Adagrasib
The serum concentration of Selumetinib can be increased when it is combined with Adagrasib.
Level 2 evidence
Adalimumab
The metabolism of Selumetinib can be increased when combined with Adalimumab.
Level 1 evidence
Adenine
The metabolism of Selumetinib can be decreased when combined with Adenine.
Level 2 evidence
Afatinib
Afatinib may decrease the excretion rate of Selumetinib which could result in a higher serum level.
Level 2 evidence
Aficamten
The metabolism of Aficamten can be decreased when combined with Selumetinib.
Level 2 evidence
Enter your NPI to unlock 14 major interactions for Koselugo
Koselugo (Selumetinib) has 724 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Koselugo (Selumetinib) has 133 major, 495 moderate, and 96 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Koselugo. Always confirm against the full prescribing information.