What is the dosage of Krystexxa?

Krystexxa is available in 1 dosages, including 8 mg/ml Injection 1 ml

What is Krystexxa made of?

Krystexxa contains pegloticase which is a Uric Acid-specific Enzyme

How is Krystexxa administered?

Krystexxa is administered as a Injectable

Krystexxa Prescribing & Dosing Schedule

Dosage & Administration

* Recommended Dosage: The recommended dosage is KRYSTEXXA 8 mg every two weeks given as an intravenous infusion, co-administered with weekly methotrexate 15 mg orally. KRYSTEXXA alone may be used in patients for whom methotrexate is contraindicated or not clinically appropriate.
* Methotrexate with folic acid or folinic acid supplementation should be initiated at least 4 weeks prior to initiating, and throughout treatment with KRYSTEXXA.
* Discontinue oral urate-lowering agents before starting KRYSTEXXA.
* Monitor serum uric acid levels before each infusion.
* Pre-medicate patients with antihistamines and corticosteroids.
* KRYSTEXXA must be diluted prior to use.
* Do not administer as an intravenous push or bolus. The KRYSTEXXA admixture should only be administered by intravenous infusion over no less than 120 minutes via gravity feed, syringe-type pump, or infusion pump.

Get Your Patient on Krystexxa

See your patient's specific prior authorization requirements including coverage restrictions and step therapies

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Krystexxa Prescribing Information

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Report Adverse Event

Krystexxa Prior Authorization Resources

Most recent state uniform prior authorization forms

Verified: Sep 24, 2024Arizona - Uniform Prior Authorization Form

Verified: Sep 24, 2024Colorado - Uniform Prior Authorization Form

Verified: Sep 24, 2024Hawaii - Uniform Prior Authorization Form

Verified: Sep 24, 2024Illinois - Uniform Prior Authorization Form

Verified: Sep 24, 2024Indiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Louisiana - Uniform Prior Authorization Form

Verified: Sep 24, 2024Minnesota - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Hampshire - Uniform Prior Authorization Form

Verified: Sep 24, 2024New Mexico - Uniform Prior Authorization Form

Verified: Sep 24, 2024Oregon - Uniform Prior Authorization Form

Verified: Sep 24, 2024Texas - Uniform Prior Authorization Form

Verified: Oct 05, 2024Washington - Uniform Prior Authorization Form

Verified: Oct 05, 2024Wisconsin - Uniform Prior Authorization Form

Complete Letter of Medical Necessity

PA Guide

Benefits investigation

Krystexxa Patient Enrollment Form

Krystexxa Patient Enrollment Form - Online

Krystexxa Preferred Pharmacy

Pharmacy List

Krystexxa Financial Assistance Options

Copay savings program

Krystexxa Patient Enrollment Form

Krystexxa Patient Enrollment Form - Online

Enroll in Patient Savings Program

Learn More

Overview

Reduce patient OOP costs for drug (and occasionally for drug administration/infusion costs or drug-related test costs)

Patient benefit

A portion (or all) of patient OOP (deductible, copay), typically up to monthly and/or annual max

Patient eligibility

Patient must enroll or activate (may permit HCPs to enroll on patient’s behalf for HCP-administered drugs)
Generally, must have commercial insurance (rarely, may permit uninsured patients to use)
May never be used with government insurance

How to sign up

Cards may be downloadable digital cards or hard copies
Some pharmacos offer debit cards with pre-loaded copay benefit
Typically, available through multiple channels (e.g., rep to HCP to patient; pharmacy to patient; patient via website, Hub live agent, or copay vendor (live agent or IVR); patient and HCP via Hub enrollment form)
Some HCP-administered product programs permit HCPs to enroll on a patient’s behalf through via Hub form