Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Krystexxa. Always confirm against the full prescribing information.
23 interactions
Bendroflumethiazide
The therapeutic efficacy of Pegloticase can be decreased when used in combination with Bendroflumethiazide.
Level 1 evidence
Chlorothiazide
The therapeutic efficacy of Pegloticase can be decreased when used in combination with Chlorothiazide.
Level 1 evidence
Hydrochlorothiazide
The therapeutic efficacy of Pegloticase can be decreased when used in combination with Hydrochlorothiazide.
Level 1 evidence
Hydroflumethiazide
The therapeutic efficacy of Pegloticase can be decreased when used in combination with Hydroflumethiazide.
Level 1 evidence
Polythiazide
The therapeutic efficacy of Pegloticase can be decreased when used in combination with Polythiazide.
Level 1 evidence
Certolizumab pegol
The therapeutic efficacy of Pegloticase can be decreased when used in combination with Certolizumab pegol.
Level 2 evidence
Damoctocog alfa pegol
The therapeutic efficacy of Damoctocog alfa pegol can be decreased when used in combination with Pegloticase.
Level 2 evidence
Elapegademase
The therapeutic efficacy of Elapegademase can be decreased when used in combination with Pegloticase.
Level 2 evidence
Methotrexate
The serum concentration of Pegloticase can be increased when it is combined with Methotrexate.
Level 1 evidence
Methoxy polyethylene glycol-epoetin beta
The therapeutic efficacy of Pegloticase can be decreased when used in combination with Methoxy polyethylene glycol-epoetin beta.
Level 2 evidence
Pegaspargase
The therapeutic efficacy of Pegloticase can be decreased when used in combination with Pegaspargase.
Level 2 evidence
Pegfilgrastim
The therapeutic efficacy of Pegloticase can be decreased when used in combination with Pegfilgrastim.
Level 2 evidence
Enter your NPI to unlock 3 major interactions for Krystexxa
Krystexxa (Pegloticase) has 23 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Krystexxa (Pegloticase) has 3 major, 5 moderate, and 15 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Krystexxa. Always confirm against the full prescribing information.