Kuvan (Sapropterin Dihydrochloride) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Kuvan. Always confirm against the full prescribing information.
100 interactions
Afatinib
The serum concentration of Afatinib can be increased when it is combined with Sapropterin.
Level 2 evidence
Ambrisentan
The serum concentration of Ambrisentan can be increased when it is combined with Sapropterin.
Level 2 evidence
Apixaban
The serum concentration of Apixaban can be increased when it is combined with Sapropterin.
Level 2 evidence
Avanafil
Sapropterin may increase the hypotensive activities of Avanafil.
Level 1 evidence
Belantamab mafodotin
The serum concentration of Belantamab mafodotin can be increased when it is combined with Sapropterin.
Level 2 evidence
Belinostat
The serum concentration of Belinostat can be increased when it is combined with Sapropterin.
Level 2 evidence
Berotralstat
The serum concentration of Berotralstat can be increased when it is combined with Sapropterin.
Level 1 evidence
Betrixaban
The serum concentration of Betrixaban can be increased when it is combined with Sapropterin.
Level 1 evidence
Bisoprolol
The serum concentration of Bisoprolol can be increased when it is combined with Sapropterin.
Level 2 evidence
Bosutinib
The serum concentration of Bosutinib can be increased when it is combined with Sapropterin.
Level 1 evidence
Brentuximab vedotin
The serum concentration of Brentuximab vedotin can be increased when it is combined with Sapropterin.
Level 2 evidence
Canagliflozin
The serum concentration of Canagliflozin can be increased when it is combined with Sapropterin.
Level 2 evidence
Enter your NPI to unlock 23 major interactions for Kuvan
Kuvan (Sapropterin Dihydrochloride) has 155 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Kuvan (Sapropterin Dihydrochloride) has 36 major, 113 moderate, and 6 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Kuvan. Always confirm against the full prescribing information.