Letrozole Drug Interactions: 74 Major, 220 Moderate
Letrozole Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Letrozole. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Letrozole can be increased when combined with Abatacept.
Level 1 evidence
Abrocitinib
The metabolism of Abrocitinib can be decreased when combined with Letrozole.
Level 2 evidence
Adalimumab
The metabolism of Letrozole can be increased when combined with Adalimumab.
Level 1 evidence
Aficamten
The metabolism of Aficamten can be decreased when combined with Letrozole.
Level 2 evidence
Albendazole
The metabolism of Albendazole can be decreased when combined with Letrozole.
Level 2 evidence
Alendronic acid
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Alendronic acid is combined with Letrozole.
Level 2 evidence
Amitriptyline
The metabolism of Amitriptyline can be decreased when combined with Letrozole.
Level 2 evidence
Amphotericin B
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Amphotericin B is combined with Letrozole.
Level 2 evidence
Anakinra
The metabolism of Letrozole can be increased when combined with Anakinra.
Level 1 evidence
Apalutamide
The serum concentration of Letrozole can be decreased when it is combined with Apalutamide.
Level 1 evidence
Apixaban
The metabolism of Apixaban can be decreased when combined with Letrozole.
Level 2 evidence
Apremilast
The metabolism of Letrozole can be increased when combined with Apremilast.
Level 1 evidence
Enter your NPI to unlock 12 major interactions for Letrozole
Letrozole has 636 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Letrozole has 74 major, 220 moderate, and 342 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Letrozole. Always confirm against the full prescribing information.