Leucovorin Calcium Drug Interactions: 3 Major, 14 Moderate
Leucovorin Calcium Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Leucovorin Calcium. Always confirm against the full prescribing information.
22 interactions
Capecitabine
The serum concentration of Capecitabine can be increased when it is combined with Leucovorin.
Level 1 evidence
Colestipol
The serum concentration of Leucovorin can be decreased when it is combined with Colestipol.
Level 1 evidence
Dapsone
The therapeutic efficacy of Dapsone can be decreased when used in combination with Leucovorin.
Level 2 evidence
Fosphenytoin
The serum concentration of Fosphenytoin can be decreased when it is combined with Leucovorin.
Level 1 evidence
Glucarpidase
The serum concentration of the active metabolites of Leucovorin can be reduced when Leucovorin is used in combination with Glucarpidase resulting in a loss in efficacy.
Level 1 evidence
Methotrexate
The therapeutic efficacy of Methotrexate can be decreased when used in combination with Leucovorin.
Level 2 evidence
Pafolacianine
Leucovorin may decrease effectiveness of Pafolacianine as a diagnostic agent.
Level 1 evidence
Pemetrexed
The therapeutic efficacy of Pemetrexed can be decreased when used in combination with Leucovorin.
Level 2 evidence
Phenytoin
The serum concentration of Phenytoin can be decreased when it is combined with Leucovorin.
Level 1 evidence
Pralatrexate
The therapeutic efficacy of Pralatrexate can be decreased when used in combination with Leucovorin.
Level 2 evidence
Primidone
The serum concentration of Primidone can be decreased when it is combined with Leucovorin.
Level 1 evidence
Proguanil
The therapeutic efficacy of Proguanil can be decreased when used in combination with Leucovorin.
Level 2 evidence
Enter your NPI to unlock 3 major interactions for Leucovorin Calcium
Leucovorin Calcium has 22 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Leucovorin Calcium has 3 major, 14 moderate, and 5 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Leucovorin Calcium. Always confirm against the full prescribing information.