Levocetirizine Dihydrochloride
Levocetirizine Dihydrochloride Prescribing Information
Levocetirizine dihydrochloride is available as 2.5 mg/5 mL (0.5 mg/mL) oral solution. Levocetirizine dihydrochloride can be taken without regard to food consumption.
Levocetirizine Dihydrochloride Oral Solution is a clear, colorless liquid containing 0.5 mg of levocetirizine dihydrochloride per mL.
The use of levocetirizine dihydrochloride is contraindicated in:
Use of levocetirizine dihydrochloride has been associated with somnolence, fatigue, asthenia, and urinary retention
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Levocetirizine dihydrochloride, the active component of Levocetirizine Dihydrochloride Oral Solution, is an orally active H
1-receptor antagonist. The chemical name is (R)-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl] ethoxy] acetic acid dihydrochloride. Levocetirizine dihydrochloride is the R enantiomer of cetirizine hydrochloride, a racemic compound with antihistaminic properties. The empirical formula of levocetirizine dihydrochloride is C
21H
25ClN
2O
3•2HCl. The molecular weight is 461.82 and the chemical structure is shown below:
Levocetirizine dihydrochloride is a white, crystalline powder and is water soluble.
Levocetirizine dihydrochloride 0.5 mg/mL oral solution is formulated as an immediate release, clear, colorless liquid. Inactive ingredients are: sodium acetate trihydrate, glacial acetic acid, maltitol solution, glycerin, methylparaben, propylparaben, sucralose, artificial grape flavor, purified water.