Lisdexamfetamine Dimesylate Drug Interactions: 28 Major
Lisdexamfetamine Dimesylate (Lisdexamfetamine Dimesylate Capsules) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Lisdexamfetamine Dimesylate. Always confirm against the full prescribing information.
100 interactions
Abiraterone
The serum concentration of dextroamphetamine, an active metabolite of Lisdexamfetamine, can be increased when used in combination with Abiraterone.
Level 1 evidence
Acebutolol
The serum concentration of dextroamphetamine, an active metabolite of Lisdexamfetamine, can be increased when used in combination with Acebutolol.
Level 1 evidence
Acetazolamide
Acetazolamide may decrease the excretion rate of Lisdexamfetamine which could result in a higher serum level.
Level 1 evidence
Acrivastine
Lisdexamfetamine may decrease the sedative activities of Acrivastine.
Level 1 evidence
Adagrasib
The serum concentration of dextroamphetamine, an active metabolite of Lisdexamfetamine, can be increased when used in combination with Adagrasib.
Level 1 evidence
Alfentanil
The risk or severity of serotonin syndrome can be increased when Alfentanil is combined with Lisdexamfetamine.
Level 1 evidence
Almotriptan
The risk or severity of serotonin syndrome can be increased when Almotriptan is combined with Lisdexamfetamine.
Level 1 evidence
Amantadine
The risk or severity of serotonin syndrome can be increased when Amantadine is combined with Lisdexamfetamine.
Level 1 evidence
Aminophylline
The risk or severity of adverse effects can be increased when Lisdexamfetamine is combined with Aminophylline.
Level 2 evidence
Amiodarone
The serum concentration of dextroamphetamine, an active metabolite of Lisdexamfetamine, can be increased when used in combination with Amiodarone.
Level 1 evidence
Amisulpride
Amisulpride may decrease the stimulatory activities of Lisdexamfetamine.
Level 2 evidence
Amitriptyline
The risk or severity of serotonin syndrome can be increased when Amitriptyline is combined with Lisdexamfetamine.
Level 1 evidence
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Lisdexamfetamine Dimesylate (Lisdexamfetamine Dimesylate Capsules) has 525 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Lisdexamfetamine Dimesylate (Lisdexamfetamine Dimesylate Capsules) has 28 major, 309 moderate, and 188 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Lisdexamfetamine Dimesylate. Always confirm against the full prescribing information.