Macrodantin Drug Interactions: 14 Major, 378 Moderate
Macrodantin (Nitrofurantoin Macrocrystals) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Macrodantin. Always confirm against the full prescribing information.
100 interactions
Abacavir
Nitrofurantoin may increase the hepatotoxic activities of Abacavir.
Level 2 evidence
Abemaciclib
Abemaciclib may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Level 2 evidence
Abiraterone
Nitrofurantoin may increase the hepatotoxic activities of Abiraterone.
Level 2 evidence
Acarbose
Acarbose may increase the hepatotoxic activities of Nitrofurantoin.
Level 2 evidence
Acenocoumarol
The risk or severity of bleeding can be increased when Nitrofurantoin is combined with Acenocoumarol.
Level 2 evidence
Acetaminophen
The risk or severity of methemoglobinemia can be increased when Acetaminophen is combined with Nitrofurantoin.
Level 2 evidence
Acetazolamide
Nitrofurantoin may increase the hepatotoxic activities of Acetazolamide.
Level 2 evidence
Acitretin
Acitretin may increase the hepatotoxic activities of Nitrofurantoin.
Level 2 evidence
Afatinib
Afatinib may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Level 2 evidence
Albendazole
Albendazole may increase the hepatotoxic activities of Nitrofurantoin.
Level 2 evidence
Alectinib
Alectinib may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
Level 2 evidence
Amikacin
Nitrofurantoin may decrease the excretion rate of Amikacin which could result in a higher serum level.
Macrodantin (Nitrofurantoin Macrocrystals) has 954 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Macrodantin (Nitrofurantoin Macrocrystals) has 14 major, 378 moderate, and 562 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Macrodantin. Always confirm against the full prescribing information.