Methadone Hydrochloride Drug Interactions: 389 Major
Methadone Hydrochloride Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Methadone Hydrochloride. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Methadone can be increased when combined with Abatacept.
Level 1 evidence
Abiraterone
The metabolism of Methadone can be decreased when combined with Abiraterone.
Level 1 evidence
Abrocitinib
The metabolism of Abrocitinib can be decreased when combined with Methadone.
Level 2 evidence
Acamprosate
The risk or severity of liver damage can be increased when Methadone is combined with Acamprosate.
Level 2 evidence
Acarbose
The risk or severity of liver damage can be increased when Acarbose is combined with Methadone.
Level 2 evidence
Acebutolol
The metabolism of Acebutolol can be decreased when combined with Methadone.
Level 2 evidence
Aceclofenac
The risk or severity of liver damage can be increased when Methadone is combined with Aceclofenac.
Level 2 evidence
Acenocoumarol
The serum concentration of Acenocoumarol can be increased when it is combined with Methadone.
Level 1 evidence
Acetaminophen
The metabolism of Acetaminophen can be decreased when combined with Methadone.
Level 2 evidence
Acetohydroxamic acid
The risk or severity of liver damage can be increased when Methadone is combined with Acetohydroxamic acid.
Level 2 evidence
Acetylsalicylic acid
The risk or severity of liver damage can be increased when Methadone is combined with Acetylsalicylic acid.
Level 2 evidence
Acitretin
The risk or severity of liver damage can be increased when Methadone is combined with Acitretin.
Level 2 evidence
Enter your NPI to unlock 25 major interactions for Methadone Hydrochloride
Methadone Hydrochloride has 1347 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Methadone Hydrochloride has 389 major, 737 moderate, and 221 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Methadone Hydrochloride. Always confirm against the full prescribing information.