Metolazone Drug Interactions: 8 Major, 299 Moderate
Metolazone Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Metolazone. Always confirm against the full prescribing information.
100 interactions
Acarbose
The therapeutic efficacy of Acarbose can be decreased when used in combination with Metolazone.
Level 2 evidence
Aceclofenac
The therapeutic efficacy of Metolazone can be decreased when used in combination with Aceclofenac.
Level 2 evidence
Acetylsalicylic acid
Acetylsalicylic acid may decrease the excretion rate of Metolazone which could result in a higher serum level.
Level 1 evidence
Alfentanil
The therapeutic efficacy of Metolazone can be decreased when used in combination with Alfentanil.
Level 2 evidence
Allopurinol
The risk of a hypersensitivity reaction to Allopurinol is increased when it is combined with Metolazone.
Level 1 evidence
Alogliptin
The therapeutic efficacy of Alogliptin can be decreased when used in combination with Metolazone.
Level 2 evidence
Amikacin
Metolazone may decrease the excretion rate of Amikacin which could result in a higher serum level.
Level 2 evidence
Amobarbital
The risk or severity of hypotension and orthostatic hypotension can be increased when Amobarbital is combined with Metolazone.
Level 2 evidence
Antipyrine
The therapeutic efficacy of Metolazone can be decreased when used in combination with Antipyrine.
Level 2 evidence
Aripiprazole
The risk or severity of hypotension can be increased when Aripiprazole is combined with Metolazone.
Level 1 evidence
Aripiprazole lauroxil
The risk or severity of hypotension can be increased when Aripiprazole lauroxil is combined with Metolazone.
Level 1 evidence
Baclofen
The risk or severity of adverse effects can be increased when Baclofen is combined with Metolazone.
Level 1 evidence
Enter your NPI to unlock 1 major interaction for Metolazone
Metolazone has 862 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Metolazone has 8 major, 299 moderate, and 555 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Metolazone. Always confirm against the full prescribing information.