Orkambi Drug Interactions: 353 Major, 1062 Moderate
Orkambi (Lumacaftor And Ivacaftor) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Orkambi. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Ivacaftor can be increased when combined with Abatacept.
Level 1 evidence
Abemaciclib
The serum concentration of Abemaciclib can be decreased when it is combined with Lumacaftor.
Level 1 evidence
Abemaciclib
The serum concentration of Abemaciclib can be increased when it is combined with Ivacaftor.
Level 1 evidence
Abiraterone
The serum concentration of Abiraterone can be increased when it is combined with Ivacaftor.
Level 1 evidence
Abiraterone
The metabolism of Abiraterone can be increased when combined with Lumacaftor.
Level 1 evidence
Abrocitinib
The serum concentration of Abrocitinib can be decreased when it is combined with Lumacaftor.
Level 1 evidence
Abrocitinib
The serum concentration of Abrocitinib can be increased when it is combined with Ivacaftor.
Level 1 evidence
Acalabrutinib
The serum concentration of Acalabrutinib can be decreased when it is combined with Lumacaftor.
Level 1 evidence
Acalabrutinib
The serum concentration of Acalabrutinib can be increased when it is combined with Ivacaftor.
Level 1 evidence
Acenocoumarol
The serum concentration of Acenocoumarol can be decreased when it is combined with Lumacaftor.
Level 1 evidence
Acenocoumarol
The serum concentration of Acenocoumarol can be increased when it is combined with Ivacaftor.
Level 1 evidence
Acetaminophen
The serum concentration of Acetaminophen can be increased when it is combined with Ivacaftor.
Level 1 evidence
Enter your NPI to unlock 18 major interactions for Orkambi
Orkambi (Lumacaftor And Ivacaftor) has 1658 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Orkambi (Lumacaftor And Ivacaftor) has 353 major, 1062 moderate, and 243 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Orkambi. Always confirm against the full prescribing information.