Thalidomide Analog

Multiple Myeloma

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Pomalidomide is a thalidomide analog. The chemical name is (RS)-4-Amino-2-(2,6-dioxo-piperidin-3-yl)-isoindoline-1,3-dione and it has the following chemical structure:</p><div class="Figure"><a name="id2989"></a><img alt="pom-chem-structure" src="pom-chem-structure.jpg"/></div><p>The empirical formula for pomalidomide is C<span class="Sub">13</span>H<span class="Sub">11</span>N<span class="Sub">3</span>O<span class="Sub">4</span> and the gram molecular weight is 273.24.</p><p>Pomalidomide is a yellow solid powder. It has limited to low solubility into organic solvents and it has low solubility in all pH solutions (about 0.01 mg/mL). Pomalidomide has a chiral carbon atom which exists as a racemic mixture of the R(+) and S(-) enantiomers.</p><p>POMALYST is available in 1-mg, 2-mg, 3-mg, and 4-mg capsules for oral administration. Each capsule contains pomalidomide as the active ingredient and the following inactive ingredients: mannitol, pregelatinized starch, and sodium stearyl fumarate. The 1-mg capsule shell contains gelatin, titanium dioxide, FD&amp;C blue 2, yellow iron oxide, white ink, and black ink. The 2-mg capsule shell contains gelatin, titanium dioxide, FD&amp;C blue 2, yellow iron oxide, FD&amp;C red 3, and white ink. The 3-mg capsule shell contains gelatin, titanium dioxide, FD&amp;C blue 2, yellow iron oxide, and white ink. The 4-mg capsule shell contains gelatin, titanium dioxide, FD&amp;C blue 1, FD&amp;C blue 2, and white ink.</p></section>

Pomalyst

pomalidomide

pomalidomide 1 MG Oral Capsule

pomalidomide 1 MG Oral Capsule [Pomalyst]

pomalidomide 2 MG Oral Capsule

pomalidomide 2 MG Oral Capsule [Pomalyst]

pomalidomide 3 MG Oral Capsule

pomalidomide 3 MG Oral Capsule [Pomalyst]

pomalidomide 4 MG Oral Capsule

pomalidomide 4 MG Oral Capsule [Pomalyst]

Psoriasis (PsO)

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