Prempro Drug Interactions: 188 Major, 922 Moderate
Prempro (Conjugated Estrogens And Medroxyprogesterone Acetate) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Prempro. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Conjugated estrogens can be increased when combined with Abatacept.
Level 1 evidence
Abemaciclib
Abemaciclib may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
Level 2 evidence
Abrocitinib
The metabolism of Abrocitinib can be decreased when combined with Medroxyprogesterone acetate.
Level 2 evidence
Acarbose
The therapeutic efficacy of Acarbose can be decreased when used in combination with Conjugated estrogens.
Level 2 evidence
Acarbose
The therapeutic efficacy of Acarbose can be decreased when used in combination with Medroxyprogesterone acetate.
Level 2 evidence
Acenocoumarol
The metabolism of Acenocoumarol can be increased when combined with Medroxyprogesterone acetate.
Level 1 evidence
Acetaminophen
The metabolism of Acetaminophen can be decreased when combined with Conjugated estrogens.
Level 2 evidence
Acetaminophen
The metabolism of Medroxyprogesterone acetate can be increased when combined with Acetaminophen.
Level 2 evidence
Acetazolamide
The metabolism of Medroxyprogesterone acetate can be increased when combined with Acetazolamide.
Level 1 evidence
Acetylsalicylic acid
The excretion of Conjugated estrogens can be decreased when combined with Acetylsalicylic acid.
Level 2 evidence
Acetylsalicylic acid
The metabolism of Acetylsalicylic acid can be decreased when combined with Medroxyprogesterone acetate.
Level 2 evidence
Acitretin
The therapeutic efficacy of Medroxyprogesterone acetate can be decreased when used in combination with Acitretin.
Level 1 evidence
Enter your NPI to unlock 14 major interactions for Prempro
Prempro (Conjugated Estrogens And Medroxyprogesterone Acetate) has 2025 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Prempro (Conjugated Estrogens And Medroxyprogesterone Acetate) has 188 major, 922 moderate, and 915 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Prempro. Always confirm against the full prescribing information.