Prozac Drug Interactions: 116 Major, 1037 Moderate
Prozac (Fluoxetine Hydrochloride) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Prozac. Always confirm against the full prescribing information.
100 interactions
Abacavir
The risk or severity of liver damage can be increased when Fluoxetine is combined with Abacavir.
Level 2 evidence
Abatacept
The metabolism of Fluoxetine can be increased when combined with Abatacept.
Level 1 evidence
Abrocitinib
The metabolism of Abrocitinib can be decreased when combined with Fluoxetine.
Level 1 evidence
Acamprosate
The risk or severity of liver damage can be increased when Fluoxetine is combined with Acamprosate.
Level 2 evidence
Acarbose
The risk or severity of hypoglycemia can be increased when Fluoxetine is combined with Acarbose.
Level 2 evidence
Acebutolol
The serum concentration of Acebutolol can be increased when it is combined with Fluoxetine.
Level 1 evidence
Acenocoumarol
The risk or severity of hemorrhage can be increased when Fluoxetine is combined with Acenocoumarol.
Level 1 evidence
Acetaminophen
The serum concentration of Acetaminophen can be increased when it is combined with Fluoxetine.
Level 1 evidence
Acetazolamide
Acetazolamide may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
Level 1 evidence
Acetohydroxamic acid
The risk or severity of liver damage can be increased when Fluoxetine is combined with Acetohydroxamic acid.
Level 2 evidence
Acetylsalicylic acid
The risk or severity of gastrointestinal bleeding can be increased when Fluoxetine is combined with Acetylsalicylic acid.
Level 1 evidence
Acitretin
The risk or severity of liver damage can be increased when Acitretin is combined with Fluoxetine.
Level 2 evidence
Enter your NPI to unlock 7 major interactions for Prozac
Prozac (Fluoxetine Hydrochloride) has 1285 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Prozac (Fluoxetine Hydrochloride) has 116 major, 1037 moderate, and 132 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Prozac. Always confirm against the full prescribing information.