Tumor Necrosis Factor Receptor Blocking Activity

Tumor Necrosis Factor Blocker

Arthritis, Rheumatoid

Colitis, Ulcerative

Crohn Disease

Spondylitis, Ankylosing

Arthritis, Psoriatic

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Infliximab, a tumor necrosis factor (TNF) blocker, is a chimeric IgG1κ monoclonal antibody (composed of human constant and murine variable regions). It has a molecular weight of approximately 149.1 kilodaltons. Infliximab is produced by a recombinant murine myeloma cell line, SP2/0.</p><p>REMICADE<span class="Bold"><span class="Sup">®</span></span> (infliximab) for injection is supplied as a sterile, preservative-free, white, lyophilized powder for intravenous infusion after reconstitution and dilution. Following reconstitution with 10 mL of Sterile Water for Injection, USP, the final concentration is 10 mg/mL and the resulting pH is approximately 7.2. Each single-dose vial contains 100 mg infliximab,  dibasic sodium phosphate, dihydrate (6.1 mg), monobasic sodium phosphate, monohydrate (2.2 mg), polysorbate 80 (0.5 mg), and sucrose (500 mg). </p></section>

REMICADE

infliximab

infliximab 100 MG Injection [Remicade]

Remicade

infliximab 100 MG Injection

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event

Prescribing Information

Medication Guide

Pharmacy List 

How To Order Remicade 

Billing & Coding Guide 

Coverage Authorization Request 

Coverage Authorization Appeals

Letter of Medical Necessity

Janssen CarePath IV Benefits Investigation & Enrollment Form

Janssen CarePath Benefits Investigation & Enrollment Form - Gastroenterology

Business Associate Agreement - HCP Office 

Patient Authorization Form - To be Signed by Patient if HCP Office has no BAA with Janssen 

Enroll in Patients Savings Program

Johnson & Johnson Patient Assistance Foundation Eligibility Check 

Other HCP Resources

Patient Brochure

Doctor Discussion Guide

Payer Coverage Decisions Guide 

Patient Affordability Options Tear Sheet 

About Remicade: Crohn's Disease

About Remicade: Pediatric Crohn's Disease

About Remicade: Ulcerative Colitis 

About Remicade: Pediatric Ulcerative Colitis

About Remicade: Rheumatoid Arthritis

About Remicade: Psoriatic Arthritis

About Remicade: Ankylosing Spondylitis

About Remicade: Plaque Psoriasis

Find an Infusion Center 

Janssen CarePath Program Support Program 

Patient Stories

FAQs About Biosimilars

Instructions For Use: Ulcerative Colitis 

Instructions For Use: Pediatric Ulcerative Colitis 

Instructions For Use: Crohn's Disease 

Instructions For Use: Pediatric Crohn's Disease 

Instructions For Use: Plaque Psoriasis

Instructions For Use: Psoriatic Arthritis 

Instructions For Use: Rheumatoid Arthritis 

Instructions For Use: Ankylosing Spondylitis 

Patient Brochure 

Doctor Discussion Guide 

Receiving Remicade: Crohn's Disease 

Receiving Remicade: Pediatric Crohn's Disease 

Receiving Remicade: Ulcerative Colitis 

Receiving Remicade: Pediatric Ulcerative Colitis 

Receiving Remicade: Rheumatoid Arthritis 

Receiving Remicade: Psoriatic Arthritis 

Receiving Remicade: Ankylosing Spondylitis

Receiving Remicade: Plaque Psoriasis