Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Samsca. Always confirm against the full prescribing information.
100 interactions
Abacavir
The risk or severity of liver damage can be increased when Abacavir is combined with Tolvaptan.
Level 2 evidence
Abemaciclib
The serum concentration of Abemaciclib can be increased when it is combined with Tolvaptan.
Level 2 evidence
Abiraterone
The risk or severity of liver damage can be increased when Abiraterone is combined with Tolvaptan.
Level 2 evidence
Acamprosate
The risk or severity of liver damage can be increased when Acamprosate is combined with Tolvaptan.
Level 2 evidence
Acarbose
The risk or severity of liver damage can be increased when Acarbose is combined with Tolvaptan.
Level 2 evidence
Acebutolol
The risk or severity of liver damage can be increased when Acebutolol is combined with Tolvaptan.
Level 2 evidence
Aceclofenac
The risk or severity of liver damage can be increased when Tolvaptan is combined with Aceclofenac.
Level 2 evidence
Acetohydroxamic acid
The risk or severity of liver damage can be increased when Acetohydroxamic acid is combined with Tolvaptan.
Level 2 evidence
Acetylsalicylic acid
Acetylsalicylic acid may decrease the excretion rate of Tolvaptan which could result in a higher serum level.
Level 1 evidence
Acitretin
The risk or severity of liver damage can be increased when Acitretin is combined with Tolvaptan.
Level 2 evidence
Acyclovir
The risk or severity of liver damage can be increased when Acyclovir is combined with Tolvaptan.
Level 2 evidence
Adefovir dipivoxil
The risk or severity of liver damage can be increased when Adefovir dipivoxil is combined with Tolvaptan.
Level 2 evidence
Enter your NPI to unlock 21 major interactions for Samsca
Samsca (Tolvaptan) has 1259 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Samsca (Tolvaptan) has 287 major, 776 moderate, and 196 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Samsca. Always confirm against the full prescribing information.