Serotonin 3 Receptor Antagonists

Serotonin-3 Receptor Antagonist

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Sancuso contains granisetron, which is a serotonin-3 (5-HT<span class="Sub">3</span>) receptor antagonist. Chemically it is 1-methyl-N-[(1R,3r,5S)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide with a molecular weight of 312.4. Its empirical formula is C<span class="Sub">18</span>H<span class="Sub">24</span>N<span class="Sub">4</span>O, while its chemical structure is:</p><table class="Noautorules" width="100%"><col align="center" valign="top" width="100%"/><tbody class="Headless"><tr><td align="center"><img alt="Chemical Structure" src="san0g-0000-01.jpg"/></td></tr><tr><td align="center">Granisetron        </td></tr></tbody></table><p>Granisetron is a white to off-white solid that is insoluble in water. The inactive ingredients are acrylate-vinylacetate copolymer, polyester, titanium dioxide, polyamide resin and polyethylene wax. Sancuso is a 52 cm<span class="Sup">2</span> thin, translucent, matrix-type transdermal system that is rectangular- shaped with rounded corners, consisting of a backing (polyester), the drug matrix (acrylate- vinylacetate copolymer) and a release liner (siliconized polyester).</p></section>

SANCUSO

granisetron

Sancuso

168 HR granisetron 0.129 MG/HR Transdermal System

168 HR granisetron 0.129 MG/HR Transdermal System [Sancuso]

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information 

Coverage Authorization Request 

Coverage Authorization Appeals 

Enroll in Patients Savings Program 

Online Sample Form 

Instructions For Use: Chemotherapy Induced Nausea & Vomiting