Sephience Drug Interactions: 2 Major, 110 Moderate
Sephience (Sepiapterin) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Sephience. Always confirm against the full prescribing information.
100 interactions
Abemaciclib
Abemaciclib may decrease the excretion rate of Sepiapterin which could result in a higher serum level.
Level 2 evidence
Afatinib
Afatinib may decrease the excretion rate of Sepiapterin which could result in a higher serum level.
Level 2 evidence
Alectinib
Alectinib may decrease the excretion rate of Sepiapterin which could result in a higher serum level.
Level 2 evidence
Apalutamide
The serum concentration of Sepiapterin can be decreased when it is combined with Apalutamide.
Level 1 evidence
Avanafil
The risk or severity of hypotension can be increased when Sepiapterin is combined with Avanafil.
Level 1 evidence
Beclomethasone dipropionate
Beclomethasone dipropionate may decrease the excretion rate of Sepiapterin which could result in a higher serum level.
Level 2 evidence
Belumosudil
Belumosudil may decrease the excretion rate of Sepiapterin which could result in a higher serum level.
Level 2 evidence
Brigatinib
Brigatinib may decrease the excretion rate of Sepiapterin which could result in a higher serum level.
Level 2 evidence
Buprenorphine
Buprenorphine may decrease the excretion rate of Sepiapterin which could result in a higher serum level.
Level 2 evidence
Caffeine
Caffeine may decrease the excretion rate of Sepiapterin which could result in a higher serum level.
Level 2 evidence
Cannabidiol
Cannabidiol may decrease the excretion rate of Sepiapterin which could result in a higher serum level.
Level 2 evidence
Capivasertib
Capivasertib may decrease the excretion rate of Sepiapterin which could result in a higher serum level.
Level 2 evidence
Enter your NPI to unlock 2 major interactions for Sephience
Sephience (Sepiapterin) has 118 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Sephience (Sepiapterin) has 2 major, 110 moderate, and 6 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Sephience. Always confirm against the full prescribing information.