Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Siklos. Always confirm against the full prescribing information.
100 interactions
Abacavir
Hydroxyurea may increase the hepatotoxic activities of Abacavir.
Level 2 evidence
Abiraterone
Hydroxyurea may increase the hepatotoxic activities of Abiraterone.
Level 2 evidence
Acarbose
Acarbose may increase the hepatotoxic activities of Hydroxyurea.
Level 2 evidence
Acetaminophen
The risk or severity of methemoglobinemia can be increased when Acetaminophen is combined with Hydroxyurea.
Level 2 evidence
Acetazolamide
Acetazolamide may increase the hepatotoxic activities of Hydroxyurea.
Level 2 evidence
Acitretin
Acitretin may increase the hepatotoxic activities of Hydroxyurea.
Level 2 evidence
Albendazole
Albendazole may increase the hepatotoxic activities of Hydroxyurea.
Level 2 evidence
Allopurinol
The risk or severity of adverse effects can be increased when Allopurinol is combined with Hydroxyurea.
Level 1 evidence
Aminosalicylic acid
The risk or severity of methemoglobinemia can be increased when Aminosalicylic acid is combined with Hydroxyurea.
Level 2 evidence
Amiodarone
Hydroxyurea may increase the hepatotoxic activities of Amiodarone.
Level 2 evidence
Amitriptyline
The metabolism of Amitriptyline can be decreased when combined with Hydroxyurea.
Level 1 evidence
Amyl Nitrite
The risk or severity of methemoglobinemia can be increased when Hydroxyurea is combined with Amyl Nitrite.
Level 2 evidence
Enter your NPI to unlock 31 major interactions for Siklos
Siklos (Hydroxyurea) has 739 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Siklos (Hydroxyurea) has 221 major, 200 moderate, and 318 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Siklos. Always confirm against the full prescribing information.