Silenor Drug Interactions: 137 Major, 628 Moderate
Silenor (Doxepin Hydrochloride) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Silenor. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Doxepin can be increased when combined with Abatacept.
Level 1 evidence
Abrocitinib
The metabolism of Abrocitinib can be decreased when combined with Doxepin.
Level 2 evidence
Acarbose
Doxepin may decrease the hypoglycemic activities of Acarbose.
Level 2 evidence
Acebutolol
Acebutolol may increase the orthostatic hypotensive activities of Doxepin.
Level 2 evidence
Acenocoumarol
The risk or severity of bleeding can be increased when Doxepin is combined with Acenocoumarol.
Level 1 evidence
Acetaminophen
The metabolism of Doxepin can be decreased when combined with Acetaminophen.
Level 2 evidence
Acetazolamide
The risk or severity of CNS depression can be increased when Acetazolamide is combined with Doxepin.
Level 2 evidence
Acoramidis
The metabolism of Doxepin can be decreased when combined with Acoramidis.
Level 2 evidence
Acyclovir
The metabolism of Doxepin can be decreased when combined with Acyclovir.
Level 2 evidence
Adagrasib
The metabolism of Doxepin can be decreased when combined with Adagrasib.
Level 2 evidence
Adalimumab
The metabolism of Doxepin can be increased when combined with Adalimumab.
Level 1 evidence
Aficamten
The metabolism of Aficamten can be decreased when combined with Doxepin.
Level 2 evidence
Enter your NPI to unlock 10 major interactions for Silenor
Silenor (Doxepin Hydrochloride) has 1323 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Silenor (Doxepin Hydrochloride) has 137 major, 628 moderate, and 558 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Silenor. Always confirm against the full prescribing information.