Simbrinza Drug Interactions: 3 Major, 296 Moderate
Simbrinza (Brinzolamide/Brimonidine Tartrate) Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Simbrinza. Always confirm against the full prescribing information.
100 interactions
Acetazolamide
Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Acetazolamide.
Level 2 evidence
Acetazolamide
The risk or severity of adverse effects can be increased when Brinzolamide is combined with Acetazolamide.
Level 2 evidence
Alfentanil
Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Alfentanil.
Level 2 evidence
Almotriptan
Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Almotriptan.
Level 2 evidence
Alosetron
Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Alosetron.
Level 2 evidence
Alprazolam
Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Alprazolam.
Level 2 evidence
Amisulpride
Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Amisulpride.
Level 2 evidence
Amitriptyline
Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Amitriptyline.
Level 2 evidence
Amobarbital
Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Amobarbital.
Level 2 evidence
Amoxapine
Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Amoxapine.
Level 2 evidence
Apalutamide
The serum concentration of Brinzolamide can be decreased when it is combined with Apalutamide.
Level 1 evidence
Apomorphine
Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Apomorphine.
Level 2 evidence
Enter your NPI to unlock 2 major interactions for Simbrinza
Simbrinza (Brinzolamide/Brimonidine Tartrate) has 424 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Simbrinza (Brinzolamide/Brimonidine Tartrate) has 3 major, 296 moderate, and 125 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Simbrinza. Always confirm against the full prescribing information.