Tumor Necrosis Factor Receptor Blocking Activity

Tumor Necrosis Factor Blocker

Arthritis, Rheumatoid

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">Golimumab is a human IgG1қ monoclonal antibody specific for human tumor necrosis factor alpha (TNFα) that exhibits multiple glycoforms with molecular masses of approximately 150 to 151 kilodaltons. Golimumab was created using genetically engineered mice immunized with human TNF, resulting in an antibody with human-derived antibody variable and constant regions. Golimumab is produced by a recombinant cell line cultured by continuous perfusion and is purified by a series of steps that includes measures to inactivate and remove viruses.</p><p>The SIMPONI ARIA   <span class="Sup">®</span>(golimumab) Injection is a sterile solution of the golimumab antibody supplied in a 4-mL glass vial for intravenous infusion. </p><p>SIMPONI ARIA is a preservative-free, colorless to light yellow solution with a pH of approximately 5.5. SIMPONI ARIA is not made with natural rubber latex. Each 4-mL vial of SIMPONI ARIA contains 50 mg golimumab, L-histidine (1.14 mg), L-histidine monohydrochloride monohydrate (6.42 mg), polysorbate 80 (0.6 mg), sorbitol (180 mg), and water for injection.</p></section>

SIMPONI ARIA

4 ML golimumab 12.5 MG/ML Injection

4 ML golimumab 12.5 MG/ML Injection [Simponi]

golimumab

Simponi

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information

Prescribing Information - Spanish

Medication Guide

Submit MSL Request

Pharmacy List

How To Order Simponi Aria

Billing & Coding Guide

Formulary Information: RA, PsA & AS

Benefits Investigation & Enrollment Form 

Janssen Patient Support Program Patient Authorization Form

Janssen Patient Support Program Patient Authorization Form - Spanish

Coverage Authorization Request

Coverage Authorization Appeals

Appeals Checklist

Appeals Checklist - Spanish

Letter of Medical Necessity

Formulary Exceptions Checklist

Formulary Exceptions Checklist - Spanish

Letter of Exception

PA Checklist

PA Checklist - Spanish

Enroll in Patient Savings Program

Other HCP Resources

About Simponi Aria

Simponi Aria Start Guide

Patient Resources

Janssen Nurse Support

Infusion Center Locator

Patient Brochure

Doctor Discussion Guide: AS

Doctor Discussion Guide: PsA

Doctor Discussion Guide: RA

Instructions For Use: RA

Instructions For Use: PsA

Instructions For Use: AS

Instructions For Use: PJIA