Simvastatin Drug Interactions: 124 Major, 908 Moderate
Simvastatin Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Simvastatin. Always confirm against the full prescribing information.
100 interactions
Abacavir
The risk or severity of liver damage can be increased when Simvastatin is combined with Abacavir.
Level 2 evidence
Abatacept
The metabolism of Simvastatin can be increased when combined with Abatacept.
Level 1 evidence
Abiraterone
The metabolism of Simvastatin can be decreased when combined with Abiraterone.
Level 1 evidence
Abrocitinib
The serum concentration of Simvastatin can be increased when it is combined with Abrocitinib.
Level 2 evidence
Acalabrutinib
The risk or severity of liver damage can be increased when Simvastatin is combined with Acalabrutinib.
Level 2 evidence
Acamprosate
The risk or severity of liver damage can be increased when Simvastatin is combined with Acamprosate.
Level 2 evidence
Acarbose
The risk or severity of liver damage can be increased when Acarbose is combined with Simvastatin.
Level 2 evidence
Acebutolol
The metabolism of Simvastatin can be decreased when combined with Acebutolol.
Level 2 evidence
Aceclofenac
The risk or severity of liver damage can be increased when Simvastatin is combined with Aceclofenac.
Level 2 evidence
Acenocoumarol
Simvastatin may increase the anticoagulant activities of Acenocoumarol.
Level 1 evidence
Acetaminophen
The risk or severity of liver damage can be increased when Acetaminophen is combined with Simvastatin.
Level 2 evidence
Acetazolamide
The risk or severity of liver damage can be increased when Simvastatin is combined with Acetazolamide.
Level 2 evidence
Enter your NPI to unlock 8 major interactions for Simvastatin
Simvastatin has 1106 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Simvastatin has 124 major, 908 moderate, and 74 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Simvastatin. Always confirm against the full prescribing information.