Cyclooxygenase Inhibitors

Nonsteroidal Anti-inflammatory Drug

Cyclooxygenase Inhibitor

Conjunctivitis, Allergic

Inflammation

Pain

Photophobia

<section class="Section" data-sectioncode="34089-3"><a name="s_1100"></a><a name="section-10"></a><h1>11 DESCRIPTION</h1>SPRIX (ketorolac tromethamine) Nasal Spray is a member of the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs, available as a clear, colorless to yellow solution packaged in a glass vial with a snap on spray pump that delivers 15.75 mg ketorolac tromethamine per spray and is intended for intranasal administration. The chemical name is (±)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1). The molecular weight is 376.41.Its molecular formula is C19H24N2O6(C15H13NO3•C4H11NO3), and it has the following chemical structure.<img alt="Chemical Structure" src="sprix-01.jpg"/>Ketorolac tromethamine is highly water-soluble, allowing its formulation in an aqueous nasal spray product at pH 7.2.The inactive ingredients in SPRIX include: edetate disodium (EDTA), monobasic potassium phosphate, sodium hydroxide, and water for injection.</section>

Sprix

ketorolac tromethamine 15.8 MG/ACTUAT Metered Dose Nasal Spray

ketorolac tromethamine 15.8 MG/ACTUAT Metered Dose Nasal Spray [Sprix]

ketorolac tromethamine

ketorolac

Psoriasis (PsO)

Psoriatic Arthritis (PsA)

Ankylosing Spondylitis (AS)

Nonradiographic Axial Spondyloarthritis

Taltz

Juvenile Idiopathic Arthritis

Hidradenitis Suppurativa (HS)

Cosentyx

Siliq

Tremfya

Crohn's Disease (CD)

Ulcerative Colitis (UC)

Stelara

Skyrizi

Ilumya

Migraine

Cluster Headache

Migraine Prevention

Emgality

Qulipta

Acute Migraine

Ubrelvy

Nurtec ODT

Vyepti

Aimovig

Ajovy

Breast Cancer: HR+ (HER2-)

Verzenio

Ibrance

Kisqali

Atopic Dermatitis (Eczema)

Cibinqo

Eucrisa

Asthma (injectable)

Asthma OCS Dependent

Nasal Polyposis

Eosinophilic Esophagitis (EoE)

Prurigo Nodularis

Dupixent

Opzelura

Adbry

NSCLC ALK+ OR ROS1+ Disease

Lorbrena

Alecensa

Alunbrig

NSCLC cMET Mutation

Xalkori

Rheumatoid Arthritis (RA)

Xeljanz

Uveitis

Graft Versus Host Disease (GVHD)

Orencia

COVID-19 Treatment

Alopecia Areata

Olumiant

Multiple Sclerosis (MS)

Secondary Progressive Multiple Sclerosis

Zeposia

Rinvoq

Entyvio

Report Adverse Event 

Prescribing Information

Medication Guide 

Pharmacy List 

Coverage Authorization Request 

Coverage Authorization Appeals 

Sprix Direct Prescription Form 

Enroll in Patient Savings Program 

Other HCP Resources 

Other HCP Resources: Videos 

About Sprix 

Instructions For Use: Pain Management 

Patient Brochure 

Patient Brochure - Spanish 

Doctor Discussion Guide 