Tramadol Hydrochloride Drug Interactions: 48 Major
Tramadol Hydrochloride Drug Interactions
Check all documented drug-to-drug interactions. Major, moderate, and minor interactions with descriptions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Tramadol Hydrochloride. Always confirm against the full prescribing information.
100 interactions
Abatacept
The metabolism of Tramadol can be increased when combined with Abatacept.
Level 1 evidence
Abiraterone
The metabolism of Tramadol can be decreased when combined with Abiraterone.
Level 1 evidence
Acalabrutinib
The metabolism of Tramadol can be decreased when combined with Acalabrutinib.
Level 1 evidence
Acebutolol
The metabolism of Tramadol can be decreased when combined with Acebutolol.
Level 1 evidence
Acenocoumarol
The therapeutic efficacy of Acenocoumarol can be increased when used in combination with Tramadol.
Level 1 evidence
Acetazolamide
The metabolism of Tramadol can be decreased when combined with Acetazolamide.
Level 1 evidence
Adalimumab
The metabolism of Tramadol can be increased when combined with Adalimumab.
Level 1 evidence
Adenine
The metabolism of Tramadol can be decreased when combined with Adenine.
Level 2 evidence
Aldesleukin
The metabolism of Tramadol can be decreased when combined with Aldesleukin.
Level 1 evidence
Alfentanil
The risk or severity of serotonin syndrome can be increased when Alfentanil is combined with Tramadol.
Level 1 evidence
Almotriptan
The risk or severity of serotonin syndrome can be increased when Almotriptan is combined with Tramadol.
Level 1 evidence
Alosetron
The risk or severity of CNS depression can be increased when Alosetron is combined with Tramadol.
Level 1 evidence
Enter your NPI to unlock 5 major interactions for Tramadol Hydrochloride
Tramadol Hydrochloride has 1199 documented drug interactions. Always review the full list with a pharmacist before co-prescribing.
Tramadol Hydrochloride has 48 major, 640 moderate, and 511 minor documented interactions.
A therapy excluded from this list does not necessarily mean no interaction exists between that therapy and Tramadol Hydrochloride. Always confirm against the full prescribing information.