Depressive Disorder, Major

<section class="Section" data-sectioncode="34089-3"><a name="S11"></a><a name="section-10"></a><p></p><h1>11 DESCRIPTION</h1><p class="First">TRINTELLIX is an immediate-release tablet for oral administration that contains the beta (β) polymorph of vortioxetine hydrobromide (HBr), an antidepressant. Vortioxetine HBr is known chemically as 1-[2-(2,4-Dimethyl-phenylsulfanyl)-phenyl]-piperazine, hydrobromide. The empirical formula is C<span class="Sub">18</span> H<span class="Sub">22</span> N<span class="Sub">2</span> S, HBr with a molecular weight of 379.36 g/mol. The structural formula is:</p><div class="Figure"><img alt="Chemical Structure" src="trintellix-01.jpg"/></div><p>Vortioxetine HBr is a white to very slightly beige powder that is slightly soluble in water.</p><p>Each TRINTELLIX tablet contains 6.355 mg, 12.71 mg or 25.42 mg of vortioxetine HBr equivalent to 5 mg, 10 mg, or 20 mg of vortioxetine, respectively. The inactive ingredients in TRINTELLIX tablets include mannitol, microcrystalline cellulose, hydroxypropyl cellulose, sodium starch glycolate, magnesium stearate and film coating which consists of hypromellose, titanium dioxide, polyethylene glycol 400, iron oxide red (5 mg and 20 mg) and iron oxide yellow (10 mg).</p></section>

Trintellix

vortioxetine 10 MG Oral Tablet

vortioxetine 20 MG Oral Tablet

vortioxetine 5 MG Oral Tablet

vortioxetine

vortioxetine 10 MG Oral Tablet [Trintellix]

vortioxetine 20 MG Oral Tablet [Trintellix]

vortioxetine 5 MG Oral Tablet [Trintellix]

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